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一项评估尿布疹治疗方法的真实世界证据研究。

A real-world evidence study evaluating a treatment for nappy rash.

作者信息

Goldman Martin, Lodhi Imran

机构信息

Chief Medical Officer, Iatros Consulting, London.

Medical Director, Allergan Limited, Marlow.

出版信息

Br J Nurs. 2016;25(8):432-9. doi: 10.12968/bjon.2016.25.8.432.

DOI:10.12968/bjon.2016.25.8.432
PMID:27126752
Abstract

This retrospective open study evaluating the efficacy of Sudocrem Antiseptic Healing Cream (SAHC) in infantile nappy rash (NR) was based on real-world evidence collected using an online questionnaire that included Likert scales. Participants who had used SAHC in the past (n=2159) were recruited via social media and email. A total of 1818 respondents who had treated NR in the previous 6 months were asked to take part in the study. Over 50% of respondents saw an improvement in NR on the same day that treatment was started, and within 3 days 94.5% of respondents reported an improvement in NR. Of 1804 subjects who answered the question, 72.5% indicated that the NR had completely healed within 3 days of starting treatment and by the fifth day, 94.7% said that the NR had completely healed. A total of 71% of 1793 respondents said that an episode of NR had either no or minimal impact disrupting their normal lives, but 29% reported a noticeable impact, even though evidence suggests that mild to moderate nappy rash can be treated quickly. Based on this real-world retrospective study, the evidence suggests SAHC is rapidly effective, reduces signs and symptoms of inflammation, and heals NR.

摘要

这项回顾性开放性研究通过使用包含李克特量表的在线问卷收集真实世界证据,评估了Sudocrem抗菌愈合霜(SAHC)治疗婴儿尿布疹(NR)的疗效。过去使用过SAHC的参与者(n = 2159)通过社交媒体和电子邮件招募。共有1818名在过去6个月内治疗过NR的受访者被邀请参加该研究。超过50%的受访者在开始治疗当天就看到NR有所改善,3天内94.5%的受访者报告NR有所改善。在回答该问题的1804名受试者中,72.5%表示在开始治疗的3天内NR完全愈合,到第5天,94.7%的人表示NR已完全愈合。在1793名受访者中,共有71%的人表示一次NR发作对他们的正常生活没有影响或影响极小,但29%的人报告有明显影响,尽管有证据表明轻度至中度尿布疹可以迅速治愈。基于这项真实世界的回顾性研究,证据表明SAHC疗效迅速,可减轻炎症的体征和症状,并治愈NR。

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