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基于顺铂的同步放化疗治疗喉鳞状细胞癌后急性髓系白血病完全缓解

Complete Remission of Acute Myeloid Leukemia following Cisplatin Based Concurrent Therapy with Radiation for Squamous Cell Laryngeal Cancer.

作者信息

Mody Mayur D, Gill Harpaul S, Higgins Kristin A, Saba Nabil F, Kota Vamsi K

机构信息

Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA; Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA.

出版信息

Case Rep Hematol. 2016;2016:8581421. doi: 10.1155/2016/8581421. Epub 2016 Apr 3.

Abstract

Acute myeloid leukemia (AML) is a myeloid disorder with several established treatment regimens depending on patient and leukemic factors. Cisplatin is known to have strong leukemogenic potential and is rarely used even as salvage therapy in relapsed or refractory AML. We present a patient simultaneously diagnosed with AML and squamous cell carcinoma of the larynx, who was found to be in complete remission from AML following treatment with cisplatin based chemoradiotherapy for his laryngeal cancer.

摘要

急性髓系白血病(AML)是一种髓系疾病,根据患者和白血病因素有几种既定的治疗方案。已知顺铂具有很强的致白血病潜力,即使在复发或难治性AML的挽救治疗中也很少使用。我们报告了一名同时被诊断为AML和喉鳞状细胞癌的患者,在用基于顺铂的放化疗治疗其喉癌后,发现其AML完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7747/4834160/bca63e763bfd/CRIHEM2016-8581421.001.jpg

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