α1受体阻滞剂对无支架输尿管镜碎石术的影响。
Effect of alpha1-blockers on stentless ureteroscopic lithotripsy.
作者信息
Zhu Jianguo, Liang Yuxiang, Chen Weihong, Xu Shuxiong, Wang Yuanlin, Hu Jianxing, He Huichan, Zhong Wei-de, Sun Zhaolin
机构信息
Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
出版信息
Int Braz J Urol. 2016 Jan-Feb;42(1):101-6. doi: 10.1590/S1677-5538.IBJU.2014.0478.
OBJECTIVE
To evaluate the clinical efficiency of alpha1-adrenergic antagonists on stentless ureteroscopic lithotripsy treating uncomplicated lower ureteral stones.
MATERIALS AND METHODS
From January 2007 to January 2013, 84 patients who have uncomplicated lower ureteral stones treated by ureteroscopic intracorporeal lithotripsy with the holmium laser were analyzed. The patients were divided into two groups, group A (44 patients received indwelled double-J stents) and group B (40 patients were treated by alpha1-adrenergic antagonists without stents). All cases of group B were treated with alpha1 blocker for 1 week.
RESULTS
The mean operative time of group A was significantly longer than group B. The incidences of hematuria, flank/abdominal pain, frequency/urgency after surgery were statistically different between both groups. The stone-free rate of each group was 100%.
CONCLUSIONS
The effect of alpha1-adrenergic antagonists is more significant than indwelling stent after ureteroscopic lithotripsy in treating uncomplicated lower ureteral stones.
目的
评估α1肾上腺素能拮抗剂在无支架输尿管镜碎石术治疗单纯性输尿管下段结石中的临床疗效。
材料与方法
分析2007年1月至2013年1月期间84例接受钬激光输尿管镜体内碎石术治疗单纯性输尿管下段结石的患者。患者分为两组，A组（44例患者留置双J管）和B组（40例患者接受α1肾上腺素能拮抗剂治疗且未留置支架）。B组所有病例均接受α1阻滞剂治疗1周。
结果
A组平均手术时间显著长于B组。两组术后血尿、腰/腹痛、尿频/尿急的发生率有统计学差异。每组结石清除率均为100%。
结论
在输尿管镜碎石术后治疗单纯性输尿管下段结石方面，α1肾上腺素能拮抗剂的效果比留置支架更显著。
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