Anagnostou Theodore, Tolley David
The Scottish Lithotriptor Centre, Western General Hospital, Crewe Road South, Edinburgh, EH4 2XU, UK.
Eur Urol. 2004 Jun;45(6):714-21. doi: 10.1016/j.eururo.2003.10.018.
The contemporary management of ureteric stones is reviewed and evidence based recommendations about treatment are made. Stones measuring less than 4mm in diameter have a high chance of spontaneous passage and the main debate for optimum treatment of larger stones centres around the choice of shock wave lithotripsy or endoscopic management combined with laser fragmentation. Treatment recommendations should be based on patient preference, published evidence, local audit (surgeon expertise and availability of equipment) and cost. Artificial Neural Networks could become a useful tool for prediction of treatment outcome for ureteric stones, and further research is needed to clarify this potential. ESWL is less effective than ureteroscopy but it may prevent the need for more invasive treatment in a substantial proportion of patients. It should only be considered as initial treatment in patients with stones less than 10mm in size. The routine use of stents should be avoided as both fragmentation and stone free rates are noticeably lower. For larger stones, initial laser ureteroscopy serves better both for proximal or distal calculi and is more cost-efficient. Provided that no contraindications for general anaesthesia exist, laser ureterolithotripsy should be regarded as an excellent first line treatment modality for ureteric stone especially in greater stone burden. In the best hands, the outcome for endoscopic management of ureteric stone in all sites is better than ESWL and is cheaper, although equipment, expertise and experience are all required to achieve this superior outcome.
本文回顾了输尿管结石的当代治疗方法,并提出了基于证据的治疗建议。直径小于4mm的结石有很高的自行排出几率,对于较大结石最佳治疗方法的主要争论集中在冲击波碎石术或内镜治疗结合激光碎石的选择上。治疗建议应基于患者偏好、已发表的证据、当地审核(外科医生的专业知识和设备可用性)以及成本。人工神经网络可能成为预测输尿管结石治疗结果的有用工具,需要进一步研究以阐明这种潜力。体外冲击波碎石术(ESWL)比输尿管镜检查效果差,但它可能在很大一部分患者中避免了更具侵入性治疗的需要。它仅应被视为结石小于10mm患者的初始治疗方法。应避免常规使用支架,因为碎石率和无石率均明显较低。对于较大的结石,初始激光输尿管镜检查对近端或远端结石均效果更佳且更具成本效益。如果不存在全身麻醉的禁忌症,激光输尿管碎石术应被视为输尿管结石的一种优秀的一线治疗方式,尤其是在结石负荷较大的情况下。在最熟练的操作下,输尿管结石各个部位的内镜治疗效果优于ESWL且成本更低,尽管要实现这种卓越的效果需要设备、专业知识和经验。