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气管插管后气管狭窄的一线治疗:气管切除及一期吻合术

First-line tracheal resection and primary anastomosis for postintubation tracheal stenosis.

作者信息

Elsayed H, Mostafa A M, Soliman S, Shoukry T, El-Nori A A, El-Bawab H Y

机构信息

Ain Shams University Hospital , Cairo , Egypt.

出版信息

Ann R Coll Surg Engl. 2016 Jul;98(6):425-30. doi: 10.1308/rcsann.2016.0162. Epub 2016 May 3.

Abstract

Introduction Tracheal stenosis following intubation is the most common indication for tracheal resection and reconstruction. Endoscopic dilation is almost always associated with recurrence. This study investigated first-line surgical resection and anastomosis performed in fit patients presenting with postintubation tracheal stenosis. Methods Between February 2011 and November 2014, a prospective study was performed involving patients who underwent first-line tracheal resection and primary anastomosis after presenting with postintubation tracheal stenosis. Results A total of 30 patients (20 male) were operated on. The median age was 23.5 years (range: 13-77 years). Seventeen patients (56.7%) had had previous endoscopic tracheal dilation, four (13.3%) had had tracheal stents inserted prior to surgery and one (3.3%) had undergone previous tracheal resection. Nineteen patients (63.3%) had had a tracheostomy. Eight patients (26.7%) had had no previous tracheal interventions. The median time of intubation in those developing tracheal stenosis was 20.5 days (range: 0-45 days). The median length of hospital stay was 10.5 days (range: 7-21 days). The success rate for anastomoses was 96.7% (29/30). One patient needed a permanent tracheostomy. The in-hospital mortality rate was 3.3%: 1 patient died from a chest infection 21 days after surgery. There was no mortality or morbidity in the group undergoing first-line surgery for de novo tracheal lesions. Conclusions First-line tracheal resection with primary anastomosis is a safe option for the treatment of tracheal stenosis following intubation and obviates the need for repeated dilations. Endoscopic dilation should be reserved for those patients with significant co-morbidities or as a temporary measure in non-equipped centres.

摘要

引言

插管后气管狭窄是气管切除重建最常见的适应证。内镜扩张几乎总会导致复发。本研究调查了对插管后气管狭窄的合适患者进行的一线手术切除和吻合术。

方法

2011年2月至2014年11月,对插管后气管狭窄患者进行一线气管切除及一期吻合术的患者进行了一项前瞻性研究。

结果

共30例患者(20例男性)接受了手术。中位年龄为23.5岁(范围:13 - 77岁)。17例患者(56.7%)曾接受过内镜下气管扩张,4例(13.3%)在手术前曾插入气管支架,1例(3.3%)曾接受过气管切除。19例患者(63.3%)曾行气管切开术。8例患者(26.7%)此前未接受过气管干预。发生气管狭窄患者的中位插管时间为20.5天(范围:0 - 45天)。中位住院时间为10.5天(范围:7 - 21天)。吻合成功率为96.7%(29/30)。1例患者需要永久性气管切开术。住院死亡率为3.3%:1例患者术后21天死于肺部感染。对于原发性气管病变接受一线手术的组中无死亡或并发症发生。

结论

一线气管切除并一期吻合术是治疗插管后气管狭窄的安全选择,无需反复扩张。内镜扩张应保留给有严重合并症的患者或作为非配备完善中心的临时措施。

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