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气管插管后气管狭窄。治疗与结果。

Postintubation tracheal stenosis. Treatment and results.

作者信息

Grillo H C, Donahue D M, Mathisen D J, Wain J C, Wright C D

机构信息

General Thoracic Surgical Unit, Massachusetts General Hospital, Boston 02114.

出版信息

J Thorac Cardiovasc Surg. 1995 Mar;109(3):486-92; discussion 492-3. doi: 10.1016/S0022-5223(95)70279-2.

Abstract

A total of 503 patients underwent 521 tracheal resections and reconstructions for postintubation stenosis from 1965 through 1992. Fifty-three had had prior attempts at surgical resection, 51 others had undergone various forms of tracheal or laryngeal repair, and 45 had had laser treatment. There were 251 cuff lesions, 178 stomal lesions, 38 at both levels, and 36 of indeterminate origin. Sixty-two patients with major laryngeal injuries required complete resection of anterior cricoid cartilage and anastomosis of trachea to thyroid cartilage, and 117 had tracheal anastomosis to the cricoid. A cervical approach was used in 350, cervicomediastinal in 145, and transthoracic in 8. Length of resection was 1.0 to 7.5 cm. Forty-nine had laryngeal release to reduce anastomotic tension. A total of 471 patients (93.7%) had good (87.5%) or satisfactory (6.2%) results. Eighteen of 37 whose operation failed underwent a second reconstruction. Eighteen required postoperative tracheostomy or T-tube insertion for extensive or multilevel disease. Twelve died (2.4%). The most common complication, suture line granulations (9.7%), has almost vanished with the use of absorbable sutures. Wound infection occurred in 15 (3%) and glottic dysfunction in 11 (2.2%). Five had postoperative innominate artery hemorrhage. Resection and reconstruction offer optimal treatment for postintubation tracheal stenosis.

摘要

1965年至1992年间,共有503例患者因插管后狭窄接受了521次气管切除和重建手术。其中53例曾接受过手术切除尝试,51例接受过各种形式的气管或喉部修复,45例接受过激光治疗。有251例袖带病变,178例吻合口病变,38例两者均有,36例病因不明。62例喉部严重损伤患者需要完全切除环状软骨前部并将气管与甲状软骨吻合,117例进行气管与环状软骨吻合。350例采用颈部入路,145例采用颈纵隔入路,8例采用经胸入路。切除长度为1.0至7.5厘米。49例进行喉部松解以减轻吻合口张力。共有471例患者(93.7%)取得了良好(87.5%)或满意(6.2%)的结果。37例手术失败的患者中有18例进行了二次重建。18例因病变广泛或多节段病变术后需要气管造口或插入T形管。12例死亡(2.4%)。最常见的并发症是缝线处肉芽组织增生(9.7%),随着可吸收缝线的使用,这种情况几乎消失。15例发生伤口感染(3%),11例发生声门功能障碍(2.2%)。5例术后无名动脉出血。切除和重建为插管后气管狭窄提供了最佳治疗方法。

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