Amberg David C, Burke Daniel J
Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York 13210;
Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908-0733.
Cold Spring Harb Protoc. 2016 May 2;2016(5):2016/5/pdb.top077628. doi: 10.1101/pdb.top077628.
The budding yeast Saccharomyces cerevisiae is an outstanding experimental model organism that has been exploited since the early part of the twentieth century for studies in biochemistry and genetics. It has been the premiere experimental system for modern functional genomics and continues to make important contributions to many areas of biology. Here we discuss its many virtues as an organism for classical genetic research.
出芽酵母酿酒酵母是一种杰出的实验模式生物,自20世纪初以来就被用于生物化学和遗传学研究。它一直是现代功能基因组学的首要实验系统,并继续在生物学的许多领域做出重要贡献。在此,我们讨论其作为经典遗传学研究生物体的诸多优点。