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胸主动脉假性动脉瘤的血管内封堵:一种适用于不适宜手术或支架置入患者的联合器械封堵和弹簧圈栓塞技术

Endovascular closure of thoracic aortic pseudoaneurysms: A combined device occlusion and coil embolization technique in patients unsuitable for surgery or stenting.

作者信息

Lyen Stephen M, Rodrigues Jonathan C L, Manghat Nathan E, Hamilton Mark C K, Turner Mark

机构信息

Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Upper Maudlin Street, Bristol, BS2 8HW.

出版信息

Catheter Cardiovasc Interv. 2016 Dec;88(7):1155-1169. doi: 10.1002/ccd.26558. Epub 2016 May 3.

Abstract

OBJECTIVES

Our aim was to retrospectively evaluate non-stent graft closure of ascending aortic pseudoaneurysms at our center over a 10-year period, and describe a combined device occlusion and coil embolization technique.

BACKGROUND

Aortic pseudoaneurysms (APAs) are a rare complication post cardiothoracic surgery, but can have fatal complications. There is increasing use of percutaneous interventional techniques for occlusion of aortic pseudoaneurysms in patients who are considered unsuitable for surgery. Stent graft deployment may not be possible depending on the specific anatomy and pathology.

METHODS AND RESULTS

Retrospective evaluation of the catheter laboratory database was performed at our center and anonymized data was obtained for patients who had nonstent endovascular treatment of APAs. Twelve patients were identified with a mean age of 63 ± 16 years. Seven patients had the combined occlusion and embolization technique, only 1/7 (14.3%) died from complications related to APAs. Five patients had occlusion device only, 3/5 (60%) died of complications related to their APA. The mean survival for the patients who had a combination procedure was 33.2±.22.6 months (range, 1 - 60 months), compared to 2.7 ± 2.6 months with device closure only (note 2 patients had short follow up of <3 months).

CONCLUSIONS

We evaluate non-stent graft percutaneous closure of APAs in a high-risk patient group and provide data on the use of a novel combined occlusion device and coil embolization technique. We feel this is a viable approach to APA closure in this population but this will require larger clinical studies in the future. © 2016 Wiley Periodicals, Inc.

摘要

目的

我们的目的是回顾性评估本中心10年间升主动脉假性动脉瘤的非支架移植物闭合情况,并描述一种联合器械封堵和弹簧圈栓塞技术。

背景

主动脉假性动脉瘤(APA)是心胸外科手术后一种罕见的并发症,但可能会导致致命的并发症。对于被认为不适合手术的患者,经皮介入技术用于封堵主动脉假性动脉瘤的应用越来越多。根据具体的解剖结构和病理情况,可能无法进行支架移植物植入。

方法和结果

我们中心对导管实验室数据库进行了回顾性评估,并获得了接受APA非支架血管内治疗患者的匿名数据。共确定了12例患者,平均年龄为63±16岁。7例患者采用了联合封堵和栓塞技术,仅1/7(14.3%)死于与APA相关的并发症。5例患者仅采用封堵器械,3/5(60%)死于与APA相关的并发症。接受联合手术的患者平均生存期为33.2±22.6个月(范围1 - 60个月),而仅采用器械封堵的患者为2.7±2.6个月(注意2例患者随访时间短于3个月)。

结论

我们评估了高危患者群体中APA的非支架移植物经皮闭合情况,并提供了关于一种新型联合封堵器械和弹簧圈栓塞技术应用的数据。我们认为这是该人群中闭合APA的一种可行方法,但未来还需要更大规模的临床研究。©2016威利期刊公司。

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