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25例患者I型内漏经导管栓塞后的早期和中期结果。

Early and midterm outcomes after transcatheter embolization of type I endoleaks in 25 patients.

作者信息

Ameli-Renani Seyed, Pavlidis Vyzantios, Morgan Robert A

机构信息

Department of Radiology, St George's University Hospitals, London, United Kingdom.

Department of Radiology, St George's University Hospitals, London, United Kingdom.

出版信息

J Vasc Surg. 2017 Feb;65(2):346-355. doi: 10.1016/j.jvs.2016.06.101.

Abstract

OBJECTIVE

This study reports the technical success and follow-up results of transcatheter embolization of type I endoleak (ELI) in 25 patients after endovascular aortic repair (EVAR).

METHODS

Twenty-five patients with ELI (20 men, five women; mean age 80 years; range, 64-96 years) underwent embolization of abdominal ELI (23 proximal, 2 distal endoleaks) after EVAR. All patients were unsuitable for standard endovascular methods for treatment of ELI. The average aneurysm sac size before embolization was 8.2 cm (range, 5.3-12.9 cm). The average time between EVAR and endoleak diagnosis was 685 days (range, 1-4220 days) and from endoleak diagnosis to embolization was 27 days (range, 2-94 days). Onyx (ev3 Endovascular, Inc, Plymouth, Minn) alone or with detachable coils was used for embolization.

RESULTS

A total of 27 embolization procedures were performed, with two patients having undergone a repeat procedure. Onyx alone was used in 16 cases and Onyx and coils were used in 11. Immediate technical success with complete isolation of the endoleak on completion angiography was achieved in all procedures. Six procedural complications occurred: three puncture site hematomas and three cases of non-target Onyx embolization. None of the complications had long term sequelae. During the follow-up period (average, 311 days; range, 1-1357 days), seven patients (28%) developed endoleak recurrence, and two underwent a second embolization procedure. Of these, one has had no further endoleak recurrence, but the other developed a recurrent endoleak and died of sac rupture. Two of the other five cases of endoleak recurrence were successfully managed by other procedures, one had a persistent endoleak despite aortic cuff placement, and the other two were deemed unsuitable for further intervention. Three of the four patients with persistent endoleaks died of sac rupture. At the average follow-up time of 311 days, freedom from endoleak recurrence was 80%, and freedom from sac growth was 85%.

CONCLUSIONS

Transcatheter embolization of ELI offers a safe, feasible, and sustainable treatment option for patients who are unsuitable for standard methods of ELI treatment. Additional coil embolization before Onyx injection may result in better outcome.

摘要

目的

本研究报告25例腹主动脉腔内修复术(EVAR)后I型内漏(ELI)患者经导管栓塞治疗的技术成功率及随访结果。

方法

25例ELI患者(20例男性,5例女性;平均年龄80岁;范围64 - 96岁)在EVAR术后接受腹部ELI栓塞治疗(23例近端内漏,2例远端内漏)。所有患者均不适合采用标准的血管腔内方法治疗ELI。栓塞前动脉瘤囊平均大小为8.2 cm(范围5.3 - 12.9 cm)。EVAR与内漏诊断之间的平均时间为685天(范围1 - 4220天),从内漏诊断到栓塞的平均时间为27天(范围2 - 94天)。单独使用Onyx(ev3 Endovascular公司,明尼苏达州普利茅斯)或联合可脱卸弹簧圈进行栓塞。

结果

共进行了27次栓塞手术,2例患者接受了重复手术。16例单独使用Onyx,11例使用Onyx和弹簧圈。所有手术在完成血管造影时均实现了内漏的完全隔离,取得了即刻技术成功。发生了6例手术并发症:3例穿刺部位血肿和3例非靶血管Onyx栓塞。所有并发症均无长期后遗症。在随访期间(平均311天;范围1 - 1357天),7例患者(28%)发生内漏复发,2例接受了第二次栓塞手术。其中,1例未再发生内漏复发,但另1例出现复发性内漏并死于瘤囊破裂。另外5例内漏复发患者中有2例通过其他手术成功处理,1例尽管放置了主动脉袖带仍存在持续性内漏,另2例被认为不适合进一步干预。4例持续性内漏患者中有3例死于瘤囊破裂。在平均随访时间311天时,无内漏复发率为80%,无瘤囊增大率为85%。

结论

经导管栓塞ELI为不适合采用标准ELI治疗方法的患者提供了一种安全、可行且可持续的治疗选择。在注射Onyx前额外进行弹簧圈栓塞可能会取得更好的效果。

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