可追踪金属基药物的开发：新一代治疗剂
Development of trackable metal-based drugs: new generation of therapeutic agents.
作者信息
Bertrand Benoît, Doulain Pierre-Emmanuel, Goze Christine, Bodio Ewen
机构信息
Institut de Chimie Moléculaire, UMR 6302 CNRS Université de Bourgogne Franche-Comté, 9 avenue A. Savary, 21078 Dijon, France.
出版信息
Dalton Trans. 2016 Aug 16;45(33):13005-11. doi: 10.1039/c5dt04275e.
PMID:27142570
Abstract
In medicinal chemistry, the aim is not only to conceive ever more efficient molecules, but also to understand their mechanism of action. In very recent years, a new promising strategy was developed to tackle this issue: the conception of trackable therapeutic agents. Metal-based drugs are ideal to exploit this expanding area of research.
摘要
在药物化学领域，目标不仅是构思出效率越来越高的分子，还要理解它们的作用机制。近年来，为解决这一问题开发了一种新的有前景的策略：可追踪治疗剂的构思。金属基药物是利用这一不断扩展的研究领域的理想选择。
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