Roever Leonardo, Biondi-Zoccai Giuseppe
Departmento de Pesquisa Clínica, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.
Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Arq Bras Cardiol. 2016 Apr;106(4):333-7. doi: 10.5935/abc.20160052.
Clinical decision-making requires synthesis of evidence from literature reviews focused on a specific theme. Evidence synthesis is performed with qualitative assessments and systematic reviews of randomized clinical trials, typically covering statistical pooling with pairwise meta-analyses. These methods include adjusted indirect comparison meta-analysis, network meta-analysis, and mixed-treatment comparison. These tools allow synthesis of evidence and comparison of effectiveness in cardiovascular research.
临床决策需要综合来自聚焦于特定主题的文献综述的证据。证据综合通过定性评估和对随机临床试验的系统评价来进行,通常涵盖采用成对荟萃分析的统计合并。这些方法包括调整间接比较荟萃分析、网状荟萃分析和混合治疗比较。这些工具可用于心血管研究中的证据综合和疗效比较。