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老年胃癌患者的根治性胃切除术

Curative gastric resection for the elderly patients suffering from gastric cancer.

作者信息

Al Mansour M, Izzo L, Mazzone G, Gabriele R, Di Cello P, Basso L, Ranieri E, Costi U, Jovanovic T, Izzo P

出版信息

G Chir. 2016 Jan-Feb;37(1):13-8. doi: 10.11138/gchir/2016.37.1.013.

Abstract

The improvement of the socio-economic conditions and the progress of medicine have extended the life span of the world's population and as a result, the number of patients with malignant neoplasms has increased. Gastric cancer is the third most common cancer (after lung and prostate) and the second leading cause of death caused by cancer (after lung bronchogenic cell carcinoma) in males; while it's the fifth cancer by frequency and the fourth cause of cancer death in females. It presents a peculiar geographical distribution with a lower incidence in Western Europe and North America, and higher incidence in the Far East, South America and Eastern Europe. Its incidence in Italy is 122 cases per 100000 inhabitants in males and 83 cases per 100000 inhabitants in females (in Italy). It occurs more frequently in old age, is quite rare in individuals under the age of 45. The aim of this work is to analyze the clinical and pathological characteristics of gastric carcinoma and the feasibility of curative surgery in patients over 75, identifying the factors affecting mortality, morbidity, survival and quality of life after surgery. These data have been compared with those of younger patients to assess the correct type of surgery.

摘要

社会经济条件的改善和医学的进步延长了世界人口的寿命,结果,恶性肿瘤患者的数量增加了。胃癌是第三大常见癌症(仅次于肺癌和前列腺癌),在男性中是癌症导致死亡的第二大主要原因(仅次于肺支气管源性细胞癌);而在女性中,按发病率计它是第五大癌症,是癌症死亡的第四大原因。它呈现出一种特殊的地理分布,在西欧和北美发病率较低,而在远东、南美和东欧发病率较高。在意大利,男性的发病率为每10万居民中有122例,女性为每10万居民中有83例(在意大利)。它在老年人群中更频繁发生,在45岁以下的个体中相当罕见。这项工作的目的是分析胃癌的临床和病理特征以及75岁以上患者进行根治性手术的可行性,确定影响手术后死亡率、发病率、生存率和生活质量的因素。这些数据已与年轻患者的数据进行比较,以评估正确的手术类型。

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