Victorson David, Hankin Vered, Burns James, Weiland Rebecca, Maletich Carly, Sufrin Nathaniel, Schuette Stephanie, Gutierrez Bruriah, Brendler Charles
Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Osher Center for Integrative Medicine at Northwestern, Northwestern Medicine, Chicago, IL, USA.
Psychooncology. 2017 Aug;26(8):1155-1163. doi: 10.1002/pon.4135. Epub 2016 May 3.
In a pilot randomized controlled trial, examine the feasibility and preliminary efficacy of an 8-week, mindfulness training program (Mindfulness Based Stress Reduction) in a sample of men on active surveillance on important psychological outcomes including prostate cancer anxiety, uncertainty intolerance and posttraumatic growth.
Men were randomized to either mindfulness (n = 24) or an attention control arm (n = 19) and completed self-reported measures of prostate cancer anxiety, uncertainty intolerance, global quality of life, mindfulness and posttraumatic growth at baseline, 8 weeks, 6 months and 12 months.
Participants in the mindfulness arm demonstrated significant decreases in prostate cancer anxiety and uncertainty intolerance, and significant increases in mindfulness, global mental health and posttraumatic growth. Participants in the control condition also demonstrated significant increases in mindfulness over time. Longitudinal increases in posttraumatic growth were significantly larger in the mindfulness arm than they were in the control arm.
While mindfulness training was found to be generally feasible and acceptable among participants who enrolled in the 8-week intervention as determined by completion rates and open-ended survey responses, the response rate between initial enrollment and the total number of men approached was lower than desired (47%). While larger sample sizes are necessary to examine the efficacy of mindfulness training on important psychological outcomes, in this pilot study posttraumatic growth was shown to significantly increase over time for men in the treatment group. Mindfulness training has the potential to help men cope more effectively with some of the stressors and uncertainties associated with active surveillance. Copyright © 2016 John Wiley & Sons, Ltd.
在一项初步随机对照试验中，研究一项为期8周的正念训练项目（基于正念的减压法）对处于主动监测阶段的男性样本在重要心理结果方面的可行性和初步疗效，这些心理结果包括前列腺癌焦虑、不确定性不耐受和创伤后成长。
将男性随机分为正念组（n = 24）或注意力控制组（n = 19），并在基线、8周、6个月和12个月时完成关于前列腺癌焦虑、不确定性不耐受、总体生活质量、正念和创伤后成长的自我报告测量。
正念组的参与者在前列腺癌焦虑和不确定性不耐受方面显著降低，在正念、总体心理健康和创伤后成长方面显著增加。对照组的参与者随着时间推移在正念方面也有显著增加。正念组创伤后成长的纵向增加显著大于对照组。
虽然根据完成率和开放式调查回复确定，正念训练在参加为期8周干预的参与者中总体上是可行且可接受的，但初始入组人数与最终接触到的男性总数之间的回应率低于预期（47%）。虽然需要更大的样本量来研究正念训练对重要心理结果的疗效，但在这项初步研究中，治疗组男性的创伤后成长随时间显著增加。正念训练有可能帮助男性更有效地应对与主动监测相关的一些压力源和不确定性。版权所有© 2016约翰·威利父子有限公司。
