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通过远程康复在家中进行帕金森病言语治疗的临床及生活质量结局:一项非劣效性随机对照试验

Clinical and Quality of Life Outcomes of Speech Treatment for Parkinson's Disease Delivered to the Home Via Telerehabilitation: A Noninferiority Randomized Controlled Trial.

作者信息

Theodoros Deborah G, Hill Anne J, Russell Trevor G

出版信息

Am J Speech Lang Pathol. 2016 May 1;25(2):214-32. doi: 10.1044/2015_AJSLP-15-0005.

DOI:10.1044/2015_AJSLP-15-0005
PMID:27145396
Abstract

PURPOSE

This study investigated the noninferiority and validity of an intensive speech treatment for people with Parkinson's disease (PD) delivered via telerehabilitation to the home. The effect of location on online delivery was also investigated.

METHOD

In this single-blinded, randomized controlled noninferiority trial, 31 participants with dysarthria associated with PD from a metropolitan area were randomly assigned to either face-to-face or online Lee Silverman Voice Treatment (LSVT LOUD). A cohort of 21 participants from nonmetropolitan areas was also recruited and treated online. Outcomes were assessed using acoustic, perceptual, and quality of life measures.

RESULTS

Noninferiority of online treatment was confirmed through comparable clinical and quality of life outcomes for the metropolitan online and face-to-face treatment groups. Significant improvements posttreatment were achieved for several acoustic, perceptual, and quality of life measures across the groups. No significant effect of online treatment location was identified.

CONCLUSIONS

Clinical and quality of life outcomes supported the noninferiority and validity of online delivery of intensive speech treatment to people with PD in the home. Future research should address the implementation of online treatment in a clinical service, cost analyses, and potentially technology-enabled clinical pathways for people with PD in order to maintain optimal communication and quality of life.

摘要

目的

本研究调查了通过远程康复在家中为帕金森病(PD)患者提供强化言语治疗的非劣效性和有效性。还研究了地点对在线治疗的影响。

方法

在这项单盲、随机对照非劣效性试验中,来自大都市地区的31名患有与PD相关构音障碍的参与者被随机分配到面对面或在线李·西尔弗曼嗓音治疗(LSVT LOUD)组。还招募了来自非大都市地区的21名参与者并进行在线治疗。使用声学、感知和生活质量测量方法评估结果。

结果

通过大都市在线和面对面治疗组可比的临床和生活质量结果证实了在线治疗的非劣效性。各治疗组在多项声学、感知和生活质量测量指标上治疗后均有显著改善。未发现在线治疗地点有显著影响。

结论

临床和生活质量结果支持在家中为PD患者在线提供强化言语治疗的非劣效性和有效性。未来的研究应解决在线治疗在临床服务中的实施、成本分析以及为PD患者潜在的技术支持临床路径,以维持最佳沟通和生活质量。

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