一名轻度β地中海贫血患者的骶前及胸内髓外造血

Presacral and intrathoracic extramedullary hematopoiesis in a patient with β thalassemia minor.

作者信息

Lalueza Antonio, Silva Carlos Patricio, Alcalá-Galiano Andrea, Arrieta Estibaliz, Cánovas José Miguel, Calero Maria Rosa, Álvarez Carlos

机构信息

Department of Internal Medicine, University Hospital 12 de Octubre, Madrid, Spain.

Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain.

出版信息

Clin Respir J. 2018 Jan;12(1):322-326. doi: 10.1111/crj.12490. Epub 2016 May 26.

DOI:10.1111/crj.12490

PMID:27148799

Abstract

Extramedullary hematopoiesis (EMH) is a rare disease characterized by the presence of hematopoietic elements outside the bone marrow as a compensatory phenomenon in several hematological diseases, including thalassemia. We report a 64-year-old man with epigastric pain of 3-months' duration radiated to the back. Imaging workup showed multiple paravertebral, retrosternal and presacral masses. Cytology findings obtained by CT-guided FNAC were compatible with the diagnosis of EMH. Peripheral blood smear confirmed the presence of β-thalassemia.

摘要

髓外造血（EMH）是一种罕见疾病，其特征是在骨髓外出现造血成分，作为包括地中海贫血在内的几种血液系统疾病的一种代偿现象。我们报告一名64岁男性，有持续3个月的上腹部疼痛并放射至背部。影像学检查显示多个椎旁、胸骨后和骶前肿块。通过CT引导下细针穿刺抽吸活检（FNAC）获得的细胞学检查结果与EMH的诊断相符。外周血涂片证实存在β地中海贫血。