Entezam A, Khandaker M U, Amin Y M, Ung N M, Bradley D A, Maah J, Safari M J, Moradi F
Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Clinical Oncology Unit, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
PLoS One. 2016 May 5;11(5):e0153913. doi: 10.1371/journal.pone.0153913. eCollection 2016.
Study has been made of the thermoluminescence (TL) response of silica-based Ge-doped cylindrical, flat and photonic crystal fibres (referred to herein as PCF-collapsed) to electron (6, 12 and 20 MeV) and photon (6, 10 MV) irradiation and 1.25 MeV γ-rays, for doses from 0.1 Gy to 100 Gy. The electron and photon irradiations were delivered through use of a Varian Model 2100C linear accelerator located at the University of Malaya Medical Centre and γ-rays delivered from a 60Co irradiator located at the Secondary Standard Dosimetry Laboratory (SSDL), Malaysian Nuclear Agency. Tailor-made to be of various dimensions and dopant concentrations (6-10% Ge), the fibres were observed to provide TL yield linear with radiation dose, reproducibility being within 1-5%, with insensitivity to energy and angular variation. The sensitivity dependency of both detectors with respect to field size follows the dependency of the output factors. For flat fibres exposed to 6 MV X-rays, the 6% Ge-doped fibre provided the greatest TL yield while PCF-collapsed showed a response 2.4 times greater than that of the 6% Ge-doped flat fibres. The response of cylindrical fibres increased with core size. The fibres offer uniform response, high spatial resolution and sensitivity, providing the basis of promising TL systems for radiotherapy applications.
研究了掺锗的圆柱形、扁平形和光子晶体光纤(本文称为PCF - 塌陷光纤)对电子(6、12和20 MeV)、光子(6、10 MV)辐照以及1.25 MeV γ射线的热释光(TL)响应,剂量范围为0.1 Gy至100 Gy。电子和光子辐照通过位于马来亚大学医学中心的Varian 2100C型直线加速器进行,γ射线由位于马来西亚核机构二级标准剂量学实验室(SSDL)的60Co辐照器提供。这些光纤经过定制,具有各种尺寸和掺杂浓度(6 - 10%锗),观察发现它们的TL产额与辐射剂量呈线性关系,重现性在1 - 5%以内,对能量和角度变化不敏感。两种探测器对射野大小的灵敏度依赖性遵循输出因子的依赖性。对于暴露于6 MV X射线的扁平光纤,6%锗掺杂的光纤提供了最大的TL产额,而PCF - 塌陷光纤的响应比6%锗掺杂的扁平光纤大2.4倍。圆柱形光纤的响应随纤芯尺寸增加。这些光纤具有均匀的响应、高空间分辨率和灵敏度,为放射治疗应用中前景广阔的TL系统提供了基础。