Department of Anaesthesiology, University Medical Centre Mainz, Mainz, Germany.
Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre of the Johannes Gutenberg-University, Mainz, Germany.
Anaesthesia. 2016 Jul;71(7):814-22. doi: 10.1111/anae.13496. Epub 2016 May 6.
We compared the Enk Fiberoptic Atomizer Set(™) with boluses of topical anaesthesia administered via the working channel during awake fibreoptic tracheal intubation in 96 patients undergoing elective surgery. Patients who received topical anaesthesia via the atomiser, compared with boluses via the fibreoptic scope, reported a better median (IQR [range]) level of comfort: 1 (1-3 [1-10]) vs. 4 (2-6 [1-10]), p < 0.0001; experienced a reduced total number of coughs: 6 (3-10 [0-34]) vs. 11 (6-13 [0-25]), p = 0.0055; and fewer distinct coughing episodes: 7% vs. 27% respectively, p = 0.0133. The atomiser technique was quicker: 5 (3-6 [2-12]) min vs. 6 (5-7 [2-15]) min, p = 0.0009; and required less topical lidocaine: 100 mg (100-100 [80-160]) vs. 200 mg (200-200 [200-200]), p < 0.0001. Four weeks after nasal intubation, the incidence of nasal pain was less in the atomiser group compared with the control group (8% vs. 50%, p = 0.0015). We conclude that the atomiser was superior to bolus application for awake fibreoptic tracheal intubation.
我们比较了 Enk 纤维光导雾化器套装(™)与在清醒纤维光导气管插管期间通过工作通道给予局部麻醉剂推注的效果,共有 96 例择期手术患者参与研究。与纤维光导镜推注相比,通过雾化器给予局部麻醉的患者报告舒适度中位数(IQR [范围])更高:1(1-3 [1-10])与 4(2-6 [1-10]),p < 0.0001;咳嗽次数更少:6(3-10 [0-34])与 11(6-13 [0-25]),p = 0.0055;咳嗽次数更集中:分别为 7%和 27%,p = 0.0133。雾化器技术更快:5(3-6 [2-12])分钟与 6(5-7 [2-15])分钟,p = 0.0009;需要的局部利多卡因更少:100 毫克(100-100 [80-160])与 200 毫克(200-200 [200-200]),p < 0.0001。鼻插管 4 周后,雾化器组的鼻痛发生率明显低于对照组(8%与 50%,p = 0.0015)。我们得出结论,雾化器在清醒纤维光导气管插管中优于推注给药。