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雾化利多卡因与气管内注射(边走边喷)利多卡因在支气管镜检查中减轻疼痛和咳嗽的比较。

Comparison of Nebulized Lidocaine and Intratracheally Injected (Spray-as-you-go) Lidocaine in Pain and Cough Reduction during Bronchoscopy.

作者信息

Islamitabar Saeid, Gholizadeh Mohammad, Rakhshani Mohammad Hasan, Kazemzadeh Asghar, Tadayonfar MoosaalReza

机构信息

Student Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran.

Department of Nursing, Sabzevar University of Medical Sciences, Sabzevar, Iran.

出版信息

Tanaffos. 2022 Mar;21(3):348-353.

Abstract

BACKGROUND

Patients undergoing bronchoscopy often suffer from pain, coughing, and suffocation. Therefore, lidocaine is prescribed through various methods to induce local anesthesia. This study aimed to compare nebulized lidocaine and intratracheally injected lidocaine in pain and cough reduction during bronchoscopy.

MATERIALS AND METHODS

This clinical trial was performed on 96 patients, divided into two groups of intervention (receiving lidocaine via a nebulizer before bronchoscopy) and control (receiving lidocaine through the working channel of bronchoscope). Then, the patients᾽ cough frequency was recorded during the procedure, and the pain level was measured using a numerical rating scale at the end of the procedure. The data were analyzed with SPSS software (version 16) using the chi-square and Fisher's exact tests. Moreover, the linear and Poisson regression tests were applied to analyze the main variables in this study.

RESULTS

There was no significant difference between the two groups regarding demographic characteristics (P>0.05). Moreover, the linear regression test revealed that the intervention (nebulized lidocaine) group had significantly lower pain scores (1.54±0.08) than the control (intratracheally injected lidocaine) group (2.5±0.26) (P=0.013). In addition, the Poisson regression test showed a statistically significant difference between the intervention (35.22±2.93) and control (48.85±5.96) groups in terms of cough frequency (P<0.0001).

CONCLUSION

This study indicated that nebulized lidocaine has higher efficacy in reducing the patients᾽ pain and cough during bronchoscopy than intratracheally injected lidocaine.

摘要

背景

接受支气管镜检查的患者常遭受疼痛、咳嗽和窒息。因此,通过各种方法使用利多卡因来诱导局部麻醉。本研究旨在比较雾化利多卡因和气管内注射利多卡因在支气管镜检查期间减轻疼痛和咳嗽方面的效果。

材料与方法

本临床试验对96例患者进行,分为干预组(支气管镜检查前通过雾化器接受利多卡因)和对照组(通过支气管镜工作通道接受利多卡因)。然后,在操作过程中记录患者的咳嗽频率,并在操作结束时使用数字评分量表测量疼痛程度。使用SPSS软件(版本16)通过卡方检验和Fisher精确检验对数据进行分析。此外,应用线性和泊松回归检验来分析本研究中的主要变量。

结果

两组在人口统计学特征方面无显著差异(P>0.05)。此外,线性回归检验显示,干预组(雾化利多卡因)的疼痛评分(1.54±0.08)显著低于对照组(气管内注射利多卡因)(2.5±0.26)(P=0.013)。此外,泊松回归检验显示,干预组(35.22±2.93)和对照组(48.85±5.96)在咳嗽频率方面存在统计学显著差异(P<0.0001)。

结论

本研究表明,雾化利多卡因在支气管镜检查期间减轻患者疼痛和咳嗽方面比气管内注射利多卡因具有更高的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/10073944/e66734e567f9/Tanaffos-21-348-g001.jpg

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