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低碳水化合物饮食与米格列醇联合治疗显著改善了一例因晚期倾倒综合征导致反应性低血糖患者的餐后血糖和胰岛素水平。

Concurrent Therapy with a Low-carbohydrate Diet and Miglitol Remarkably Improved the Postprandial Blood Glucose and Insulin Levels in a Patient with Reactive Hypoglycemia due to Late Dumping Syndrome.

作者信息

Hirose Sachie, Iwahashi Yasuyuki, Seo Akane, Sumiyoshi Michitaka, Takahashi Tetsuya, Tamori Yoshikazu

机构信息

Division of Diabetes and Endocrinology, Department of Internal Medicine, Chibune General Hospital, Japan.

出版信息

Intern Med. 2016;55(9):1137-42. doi: 10.2169/internalmedicine.55.5655. Epub 2016 May 1.

Abstract

Reactive hypoglycemia induced by late dumping syndrome is often observed after gastrectomy. However, no effective therapy has yet been fully established. We herein describe a case in which concurrent therapy with a low-carbohydrate diet using low-glycemic-index food and an alpha-glucosidase inhibitor, miglitol, very effectively ameliorated the postprandial fluctuations in the blood glucose and plasma insulin levels in a patient with reactive hypoglycemia due to late dumping syndrome following total gastrectomy. The administration of miglitol under a low-carbohydrate diet using low-glycemic-index food may therefore be an ideal treatment for reactive hypoglycemia due to late dumping syndrome.

摘要

晚期倾倒综合征诱发的反应性低血糖常见于胃切除术后。然而,尚未完全确立有效的治疗方法。在此,我们描述了一例病例,对于一名因全胃切除术后晚期倾倒综合征导致反应性低血糖的患者,采用低血糖指数食物的低碳水化合物饮食与α-葡萄糖苷酶抑制剂米格列醇联合治疗,非常有效地改善了餐后血糖和血浆胰岛素水平的波动。因此,在采用低血糖指数食物的低碳水化合物饮食基础上给予米格列醇,可能是治疗晚期倾倒综合征所致反应性低血糖的理想方法。

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