Hirose Sachie, Iwahashi Yasuyuki, Seo Akane, Sumiyoshi Michitaka, Takahashi Tetsuya, Tamori Yoshikazu
Division of Diabetes and Endocrinology, Department of Internal Medicine, Chibune General Hospital, Japan.
Intern Med. 2016;55(9):1137-42. doi: 10.2169/internalmedicine.55.5655. Epub 2016 May 1.
Reactive hypoglycemia induced by late dumping syndrome is often observed after gastrectomy. However, no effective therapy has yet been fully established. We herein describe a case in which concurrent therapy with a low-carbohydrate diet using low-glycemic-index food and an alpha-glucosidase inhibitor, miglitol, very effectively ameliorated the postprandial fluctuations in the blood glucose and plasma insulin levels in a patient with reactive hypoglycemia due to late dumping syndrome following total gastrectomy. The administration of miglitol under a low-carbohydrate diet using low-glycemic-index food may therefore be an ideal treatment for reactive hypoglycemia due to late dumping syndrome.
晚期倾倒综合征诱发的反应性低血糖常见于胃切除术后。然而,尚未完全确立有效的治疗方法。在此,我们描述了一例病例,对于一名因全胃切除术后晚期倾倒综合征导致反应性低血糖的患者,采用低血糖指数食物的低碳水化合物饮食与α-葡萄糖苷酶抑制剂米格列醇联合治疗,非常有效地改善了餐后血糖和血浆胰岛素水平的波动。因此,在采用低血糖指数食物的低碳水化合物饮食基础上给予米格列醇,可能是治疗晚期倾倒综合征所致反应性低血糖的理想方法。