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双侧同时发生的膝关节肺炎球菌性败血症性关节炎:免疫系统正常,感染源不明。

Bilateral, simultaneous pneumococcal septic arthritis of the knees: a normal immune system, an unknown source.

作者信息

Whitehead-Clarke Thomas Ian, Singavarapu Raj, Gulihar Abhinav, Chettiar Krissen

机构信息

Department of General Surgery, Medway NHS Foundation Trust, Gillingham, UK.

Department of Trauma and Orthopaedics, Darent Valley Hospital, Dartford, UK.

出版信息

BMJ Case Rep. 2016 May 5;2016:bcr2016214980. doi: 10.1136/bcr-2016-214980.

Abstract

Pneumococcal septic arthritis is a rare clinical entity and is often associated with a systemic bacteraemia. A 60-year-old man was admitted with bilateral swollen, painful knees. He was feeling feverish with raised inflammatory markers. Joint aspiration yielded purulent fluid, which, when cultured, grew Streptococcus Pneumoniae bilaterally. The patient underwent repeated arthroscopic knee washouts and was treated with intravenous (IV) antibiotics. During his admission, various investigations and scans were undertaken to find an infective focus or signs of immunodeficiency; none were found. After 4 weeks of IV antibiotics and 4 knee washouts, the patient was discharged. We believe this is the only case documented of bilateral simultaneous pneumococcal septic arthritis of the knees in an immunocompetent patient with no extra-articular infective focus. This case exemplifies the importance of careful assessment of patients who present with bilateral swollen joints.

摘要

肺炎球菌性败血症性关节炎是一种罕见的临床病症,常与全身性菌血症相关。一名60岁男性因双侧膝关节肿胀、疼痛入院。他伴有发热,炎症指标升高。关节穿刺抽出脓性液体,培养后双侧均培养出肺炎链球菌。患者接受了多次关节镜下膝关节冲洗,并接受静脉注射抗生素治疗。在其住院期间,进行了各种检查和扫描以寻找感染源或免疫缺陷迹象;未发现任何异常。经过4周的静脉注射抗生素治疗和4次膝关节冲洗后,患者出院。我们认为这是有记录的唯一一例在免疫功能正常且无关节外感染源的患者中双侧同时发生肺炎球菌性败血症性关节炎的病例。该病例体现了对出现双侧关节肿胀的患者进行仔细评估的重要性。

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