Marcove R C, Lewis M M, Rosen G, Huvos A G
Clin Orthop Relat Res. 1977 Jul-Aug(126):147-52.
Osteogenic sarcoma, a highly malignant tumor of bone, is generally treated by amputation. This is a report of 19 cases of excision of the entire femur because of skip areas which are occasionally seen. The femur usually has the lowest cure rate according to site of involvement. In total femur replacement, the whole bone is removed while the limb is saved. The operation consists of isolating the neurovascular bundle and removing the knee joint and femur including some surrounding normal tissue for margin of safety. The femur and knee replacements are made entirely of metal. The resultant extremity is weak, but functional. The patients can walk without support, but their gait is better using a cane and/or an ischial weight bearing brace.
骨肉瘤是一种高度恶性的骨肿瘤,通常采用截肢治疗。本文报告了19例因偶尔出现的跳跃区域而切除整个股骨的病例。根据受累部位,股骨的治愈率通常最低。在全股骨置换中,切除整个骨头同时保留肢体。手术包括分离神经血管束,切除膝关节和股骨,包括一些周围正常组织以确保安全切缘。股骨和膝关节置换全部由金属制成。由此产生的肢体较弱,但有功能。患者可以无需支撑行走,但使用拐杖和/或坐骨承重支具时步态会更好。