Roth D E, Hodge S J, Callen J P
Division of Dermatology, University of Louisville, School of Medicine, KY 40292.
J Am Acad Dermatol. 1989 May;20(5 Pt 2):950-4. doi: 10.1016/s0190-9622(89)70117-1.
A patient who developed lentigines after prolonged ultraviolet A (UVA) exposure in a tanning booth is described. The patient had no exposure to psoralens or furocoumarins. Histologic examination of a representative lentigo revealed melanocytic hyperplasia and cytologic atypia. Increased nevocytic activity with histologic dysplasia was present in several junctional nevi excised during the period of UVA exposure. Several studies have revealed significant effects of UVA on melanocytes. Patients should be cautioned to avoid tanning bed use in view of these potentially deleterious effects.
本文描述了一名患者,其在美黑床中长时间暴露于紫外线A(UVA)后出现了雀斑样痣。该患者未接触过补骨脂素或呋喃香豆素。对一个具有代表性的雀斑样痣进行组织学检查,发现有黑素细胞增生和细胞异型性。在UVA暴露期间切除的几个交界痣中,出现了痣细胞活性增加伴组织学发育异常。多项研究揭示了UVA对黑素细胞有显著影响。鉴于这些潜在的有害影响,应告诫患者避免使用美黑床。