Gooding Holly C, Sheldrick R Christopher, Leslie Laurel K, Shah Supriya, de Ferranti Sarah D, Mackie Thomas I
Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts.
Department of Pediatrics, Tufts Medical Center, Boston, Massachusetts.
J Adolesc Health. 2016 Aug;59(2):162-70. doi: 10.1016/j.jadohealth.2016.03.027. Epub 2016 May 5.
Guidelines recommend cholesterol screening for all adolescents and young adults (AYAs) ages 17-21 years. Little is known about how screening results impact perceptions of AYA health.
We recruited 37 AYAs and 35 parents of AYAs with differing risk for abnormal cholesterol results: (1) familial hypercholesterolemia; (2) obesity; and (3) generally healthy. Participants completed quantitative health status ratings using visual analog scales (VASs) and semistructured interviews regarding three hypothetical cholesterol screening scenarios: (1) high likelihood of cardiovascular disease (CVD) before age 40 years ("high risk"); (2) some risk of CVD before age 70 years ("moderate risk"); and (3) low risk for CVD despite a strong family history of CVD ("low risk"). We analyzed VAS data with logistic regression and qualitative data with a priori and emergent coding using multiple coders.
Each group perceived all three cholesterol screening scenarios as comparatively less than perfect health; the high-risk result fell furthest from perfect health. Although there was no significant difference between AYAs and parents in VAS ratings, qualitative analyses revealed AYAs were more likely than parents to discount the impact of moderate-risk results because of longer length of time before predicted CVD.
AYAs' and parents' perceptions of the impact of cholesterol screening results on AYA health varied by presented scenario, ranging from mild to significant decreases in perceptions of AYA health. As universal cholesterol screening continues to be adopted in this age group, further studies of the real-life impact on AYA risk perceptions and subsequent behavior are warranted.
指南建议对所有17至21岁的青少年及青年(AYA)进行胆固醇筛查。关于筛查结果如何影响对AYA健康的认知,我们知之甚少。
我们招募了37名AYA以及35名AYA的父母,他们具有不同的胆固醇异常结果风险:(1)家族性高胆固醇血症;(2)肥胖;(3)一般健康。参与者使用视觉模拟量表(VAS)完成定量健康状况评分,并就三种假设的胆固醇筛查情况进行半结构化访谈:(1)40岁前心血管疾病(CVD)高风险;(2)70岁前有一定CVD风险(“中度风险”);(3)尽管有强烈的CVD家族史但CVD风险低(“低风险”)。我们使用逻辑回归分析VAS数据,并使用多个编码员对定性数据进行先验编码和新现编码。
每组都认为所有三种胆固醇筛查情况相对而言都算不上完美健康;高风险结果与完美健康的差距最大。尽管AYA和父母在VAS评分上没有显著差异,但定性分析显示,由于预测的CVD发生前时间更长,AYA比父母更有可能低估中度风险结果的影响。
AYA和父母对胆固醇筛查结果对AYA健康影响的认知因呈现的情况而异,对AYA健康的认知从轻微下降到显著下降不等。随着该年龄组继续采用普遍的胆固醇筛查,有必要进一步研究其对AYA风险认知及后续行为的现实影响。