Clinic of Cardiovascular Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Clinic for Vascular Surgery, Kantonsspital St Gallen, St Gallen, Switzerland.
J Thorac Cardiovasc Surg. 2016 Sep;152(3):810-7. doi: 10.1016/j.jtcvs.2016.03.078. Epub 2016 Apr 13.
Floating aortic thrombus is an underrecognized source of systemic emboli and carries a life-threatening risk of stroke when located in the aortic arch. Optimal treatment is not established in available guidelines. We report our experience in managing floating thrombi in the aortic arch.
Consecutive patients diagnosed with a floating aortic arch thrombus at a tertiary referral center between January 2008 and December 2014 were reviewed. Perioperative and midterm outcomes were assessed.
Ten patients (8 female) with a median age of 56 years (range, 47-82 years) were identified. Eight patients presented with a symptomatic embolic event, and 2 patients were asymptomatic. One patient presenting with stroke due to embolic occlusion of all supra-aortic vessels died 2 days after admission. Three patients (2 asymptomatic and 1 unfit for surgery) were treated conservatively by anticoagulation, leading to thrombus resolution in 2 patients. In the third patient, the thrombus persisted despite anticoagulation, resulting in recurrent embolic events. The remaining 6 patients underwent open thrombectomy of the aortic arch during deep hypothermic circulatory arrest. All patients treated by surgery had an uneventful postoperative course with no recurrent thrombus or embolic event during follow-up. Median follow-up of all patients was 17 months (range, 11-89 months).
Floating aortic arch thrombus is a dangerous source of systemic emboli. Surgical removal of the thrombus is easy to perform and followed by good clinical results. Conservative treatment with anticoagulation may be considered in asymptomatic, inoperable or high-risk patients.
漂浮性主动脉血栓是全身性栓塞的一个未被充分认识的来源,当位于主动脉弓时,会带来危及生命的中风风险。现有的指南并未确立最佳的治疗方法。我们报告了在处理主动脉弓漂浮性血栓方面的经验。
回顾了 2008 年 1 月至 2014 年 12 月在一家三级转诊中心诊断为主动脉弓漂浮性血栓的连续患者。评估了围手术期和中期结果。
确定了 10 名(8 名女性)患者,中位年龄为 56 岁(范围,47-82 岁)。8 名患者出现症状性栓塞事件,2 名患者无症状。1 名因所有主动脉以上血管栓塞性闭塞导致中风的患者在入院后 2 天死亡。3 名(2 名无症状和 1 名不适合手术)患者通过抗凝保守治疗,其中 2 名患者血栓溶解。在第 3 名患者中,尽管进行了抗凝治疗,血栓仍持续存在,并导致反复栓塞事件。其余 6 名患者在深低温循环停止期间接受了主动脉弓开放性血栓切除术。所有接受手术治疗的患者术后均无并发症,在随访期间无复发性血栓或栓塞事件。所有患者的中位随访时间为 17 个月(范围,11-89 个月)。
漂浮性主动脉弓血栓是全身性栓塞的危险来源。血栓切除术易于操作,并且临床效果良好。对于无症状、无法手术或高危患者,可以考虑抗凝保守治疗。