Short term effects of small incision lenticule extraction surgery on corneal endothelium.
作者信息
Wang Dan-Yang, Liu Man-Li, Chen Yi-Le, Zhang Xiao-Ying, Xu Yang-Tao, Wang Jian-Chao, To Chi-Ho, Wang Jian-Guo, Liu Quan
机构信息
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China; Hainan Eye Hospital, Zhongshan Ophthamic Center, Sun Yat-sen University, Haikou 570311, Hainan Province, China.
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
出版信息
Int J Ophthalmol. 2016 Apr 18;9(4):536-9. doi: 10.18240/ijo.2016.04.09. eCollection 2016.
AIM
To assess the effects of small incision lenticule extraction (SMILE) surgery on the corneal endothelium at 1d to 1mo postoperatively.
METHODS
A retrospective, observational study was conducted on 47 patients (47 eyes) who received SMILE surgery. Patients were grouped according to contact lens wear condition. The corneal endothelium was examined preoperatively and at 1d, 1wk and 1mo postoperatively. The corneal endothelium was analyzed for endothelial cell density (ECD), percentage of hexagonal cells, and coefficient of variation (CV) of cell size.
RESULTS
There were no significant decrease in the ECD, percentage of hexagonal cells or increase in CV at 1d, 1wk and 1mo postoperatively (P>0.05). However, there was a small increase of ECD by 2.88% in contact lens wearers (78.26±113.62 cell/mm(2), P<0.05).
CONCLUSION
SMILE has no significant adverse effects on the corneal ECD and morphology during 1mo follow-up time.
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