使用两种飞秒激光对准分子原位角膜磨镶术后角膜内皮细胞密度和形态的分析。
Analysis of corneal endothelial cell density and morphology after laser in situ keratomileusis using two types of femtosecond lasers.
作者信息
Tomita Minoru, Waring George O, Watabe Miyuki
机构信息
Shinagawa LASIK Center, Chiyoda-ku, Tokyo, Japan ; Department of Ophthalmology, Wenzhou Medical College, Wenzhou, China.
出版信息
Clin Ophthalmol. 2012;6:1567-72. doi: 10.2147/OPTH.S35887. Epub 2012 Sep 24.
PURPOSE
To compare two different femtosecond lasers used for flap creation during laser-assisted in situ keratomileusis (LASIK) surgery in terms of their effects on the corneal endothelium.
METHODS
We performed LASIK surgery on 254 eyes of 131 patients using IntraLase FS60 (Abbott Medical Optics, Inc, Irvine, CA; IntraLase group) and 254 eyes of 136 patients using Femto LDV (Ziemer Group AG, Port, Switzerland; LDV group) for corneal flap creation. The mean cell density, coefficient of variation, and hexagonality of the corneal endothelial cells were determined and the results were statistically compared.
RESULTS
There were no statistically significant differences in the corneal morphology between pre and post LASIK results in each group, nor were there significant differences between the results of both groups at 3 months post LASIK.
CONCLUSIONS
Both IntraLase FS60 and Ziemer Femto LDV are able to create flaps without significant adverse effects on the corneal endothelial morphology through 3 months after LASIK surgery.
目的
比较两种用于准分子原位角膜磨镶术（LASIK）手术中制作角膜瓣的不同飞秒激光对角膜内皮的影响。
方法
我们使用IntraLase FS60（雅培医疗光学公司，加利福尼亚州欧文市；IntraLase组）为131例患者的254只眼进行LASIK手术制作角膜瓣，使用Femto LDV（齐默集团股份公司，瑞士波特；LDV组）为136例患者的254只眼进行LASIK手术制作角膜瓣。测定角膜内皮细胞的平均细胞密度、变异系数和六角形细胞比例，并对结果进行统计学比较。
结果
每组LASIK术前和术后的角膜形态在统计学上无显著差异，LASIK术后3个月两组结果之间也无显著差异。
结论
IntraLase FS60和齐默Femto LDV都能够制作角膜瓣，且在LASIK手术后3个月内对角膜内皮形态无明显不良影响。
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