Hall P, Cedermark B, Swedenborg J
Department of Oncology, Karolinska Hospital, Stockholm, Sweden.
J Surg Oncol. 1989 May;41(1):39-41. doi: 10.1002/jso.2930410112.
Fifty-three implantable catheter systems (Port-A-Cath) were placed subcutaneously in 48 patients with malignant tumours. This device consists of a stainless steel chamber covered by a silicone membrane connected to a silicone catheter placed in a central vein. All systems were used for administration of chemotherapy. The mean function time was 187 days (range 0-867). Complications necessitating reoperation occurred in six patients. In three cases, the catheter occluded from thromboses. In two patients, wound dehiscence occurred, and in one a wound infection developed. In one case, the catheter was disconnected from the port. Four patients who had had the port removed later received new ports. One patient had the second port removed and was given a third catheter system. It is concluded that subcutaneously implantable injection ports constitute a safe and convenient access for long-term intravenous chemotherapy. The complication rate is low, and it should be possible to avoid most recorded complications in the future.
53个可植入式导管系统(Port-A-Cath)被皮下植入48例恶性肿瘤患者体内。该装置由一个覆盖有硅胶膜的不锈钢腔室组成,该腔室连接到一根置于中心静脉的硅胶导管。所有系统均用于化疗给药。平均使用时间为187天(范围0 - 867天)。6例患者出现需要再次手术的并发症。3例中,导管因血栓形成而堵塞。2例患者发生伤口裂开,1例出现伤口感染。1例中,导管与端口分离。4例已移除端口的患者后来接受了新的端口。1例患者移除了第二个端口并接受了第三个导管系统。结论是,皮下可植入式注射端口构成了长期静脉化疗的安全便捷通路。并发症发生率低,未来应有可能避免大多数已记录的并发症。