Hogle Susan, Boll Rose Ann, Murphy Karen, Denton David, Owens Allison, Haverlock Tamara J, Garland Marc, Mirzadeh Saed
Divisions of Nuclear Security and Isotopes Technology, Oak Ridge National Laboratory, Oak Ridge, TN 37831, United States.
Divisions of Nuclear Security and Isotopes Technology, Oak Ridge National Laboratory, Oak Ridge, TN 37831, United States.
Appl Radiat Isot. 2016 Aug;114:19-27. doi: 10.1016/j.apradiso.2016.05.002. Epub 2016 May 3.
Limited availability of (229)Th for clinical applications of (213)Bi necessitates investigation of alternative production routes. In reactor production, (229)Th is produced from neutron transmutation of (226)Ra, (228)Ra, (227)Ac and (228)Th. Irradiations of (226)Ra, (228)Ra, and (227)Ac targets at the Oak Ridge National Laboratory High Flux Isotope Reactor result in yields of (229)Th at 26 days of 74.0±7.4MBq/g, 260±10MBq/g, and 1200±50MBq/g, respectively. Intermediate radionuclide yields and cross sections are also studied.
由于用于铋-213临床应用的钍-229可用性有限,因此有必要研究其他生产途径。在反应堆生产中,钍-229由镭-226、镭-228、锕-227和钍-228的中子嬗变产生。在橡树岭国家实验室高通量同位素反应堆中对镭-226、镭-228和锕-227靶进行辐照,在26天时钍-229的产率分别为74.0±7.4MBq/g、260±10MBq/g和1200±50MBq/g。还研究了中间放射性核素的产率和截面。