Wright J M, Sachdev P S, Perkins R J, Rodriguez P
Prince Henry Hospital, Little Bay, NSW.
Med J Aust. 1989 Mar 20;150(6):339-41. doi: 10.5694/j.1326-5377.1989.tb136499.x.
Two patients with the acquired immunodeficiency syndrome (AIDS), who had no past psychiatric history, developed a mania-like illness soon after commencing treatment with zidovudine. The neurotoxic effects of zidovudine have been described previously, but to our knowledge no reports of a psychiatric disorder that is related to the drug have appeared. Our report emphasizes the need to monitor patients with AIDS for neuropsychiatric problems.