Barboza Miriane Lilian, Barbosa Alan Carlos Brisola, Spina Giovanna Domingues, Sperandio Evandro Fornias, Arantes Rodolfo Leite, Gagliardi Antonio Ricardo de Toledo, Romiti Marcello, Dourado Victor Zuniga
Universidade Federal de São Paulo, Santos, SP, Brasil.
Instituto de Medicina Cardiovascular Angiocorpore, Santos, SP, Brasil.
J Bras Pneumol. 2016 Apr;42(2):130-5. doi: 10.1590/S1806-37562015000000102.
To determine whether the level of physical activity in daily life (PADL) is associated with pulmonary function in adult smokers.
We selected 62 adult smokers from among the participants of an epidemiological study conducted in the city of Santos, Brazil. The subjects underwent forced spirometry for pulmonary function assessment. The level of PADL was assessed by the International Physical Activity Questionnaire and triaxial accelerometry, the device being used for seven days. The minimum level of PADL, in terms of quantity and intensity, was defined as 150 min/week of moderate to vigorous physical activity. Correlations between the studied variables were tested with Pearson's or Spearman's correlation coefficient, depending on the distribution of the variables. We used linear multiple regression in order to analyze the influence of PADL on the spirometric variables. The level of significance was set at 5%.
Evaluating all predictors, corrected for confounding factors, and using pulmonary function data as outcome variables, we found no significant associations between physical inactivity, as determined by accelerometry, and spirometric indices. The values for FVC were lower among the participants with arterial hypertension, and FEV1/FVC ratios were lower among those with diabetes mellitus. Obese participants and those with dyslipidemia presented with lower values for FVC and FEV1.
Our results suggest that there is no consistent association between physical inactivity and pulmonary function in adult smokers. Smoking history should be given special attention in COPD prevention strategies, as should cardiovascular and metabolic comorbidities.
确定成年吸烟者的日常生活身体活动水平(PADL)是否与肺功能相关。
我们从巴西桑托斯市进行的一项流行病学研究的参与者中选取了62名成年吸烟者。受试者接受了用于评估肺功能的用力肺活量测定。通过国际身体活动问卷和三轴加速度计评估PADL水平,该设备使用七天。就数量和强度而言,PADL的最低水平定义为每周150分钟的中等至剧烈身体活动。根据变量的分布情况,使用Pearson或Spearman相关系数检验研究变量之间的相关性。我们使用线性多元回归来分析PADL对肺活量测定变量的影响。显著性水平设定为5%。
在对混杂因素进行校正并将肺功能数据用作结果变量的情况下,评估所有预测因素时,我们发现通过加速度计确定的身体不活动与肺活量测定指标之间没有显著关联。患有动脉高血压的参与者的用力肺活量(FVC)值较低,患有糖尿病的参与者的第一秒用力呼气容积/用力肺活量(FEV1/FVC)比值较低。肥胖参与者和患有血脂异常的参与者的FVC和FEV1值较低。
我们的结果表明,成年吸烟者的身体不活动与肺功能之间没有一致的关联。在慢性阻塞性肺疾病(COPD)预防策略中,应特别关注吸烟史,以及心血管和代谢合并症。