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空气污染物与儿童肺炎住院情况:一项时间序列分析

Air pollutants and hospital admission due to pneumonia in children: a time series analysis.

作者信息

Souza Laís Salgado Vieira de, Nascimento Luiz Fernando Costa

机构信息

Department of Medicine, Universidade de Taubaté, Taubaté, SP, Brazil.

Department of Medicine, Unitau, Taubaté, SP, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2016 Apr;62(2):151-6. doi: 10.1590/1806-9282.62.02.151.

Abstract

OBJECTIVE

The aim of this study was to estimate the association between expo sure to air pollutants and hospitalization for pneumonia among children in a medium-sized city located in the sugar cane plantation region of São Paulo State.

METHODS

An ecological time-series study was conducted with daily data of hospi talization for pneumonia including children aged 10 years or younger living in Ar araquara, state of São Paulo, from January 1st, 2010, to November 30th, 2012. To es timate the association between hospitalization due to pneumonia and particulate pollutants with aerodynamic diameter less than 10 µm, nitrogen dioxide and ozone, relative risks for hospitalization according to a generalized additive model of Pois son regression, with Lags of up to five days, were calculated. A percentage increase (PI) was obtained for relative risk (IRR - increase on relative risk) of hospitalization at each 10 µg/m3 increment in each air pollutants adjusted for the remaining.

RESULTS

A total of 234 hospitalizations were recorded during these three years. There was a strong association between hospitalization and PM10 and NO2. The PI in relative risk was 15% to PM10 in Lag 0 and 7% points in Lag 1 for NO2.

CONCLUSION

There was evidence of the action of air pollutants on hospitaliza tion for pneumonia in a medium-sized city located in a region affected by air pollution from sugarcane burning and the data presented here provide subsi dies for the implementation of public policies aiming to decrease this risk.

摘要

目的

本研究旨在评估圣保罗州甘蔗种植区一座中等城市儿童接触空气污染物与因肺炎住院之间的关联。

方法

采用生态时间序列研究,纳入了2010年1月1日至2012年11月30日期间居住在圣保罗州阿拉拉夸拉市10岁及以下儿童因肺炎住院的每日数据。为了评估因肺炎住院与空气动力学直径小于10微米的颗粒物污染物、二氧化氮和臭氧之间的关联,根据泊松回归的广义相加模型计算了长达五天滞后的住院相对风险,并针对每10微克/立方米的每种空气污染物增量,在调整其余因素后获得了住院相对风险的百分比增加(PI)。

结果

这三年共记录了234例住院病例。住院与PM10和NO2之间存在密切关联。滞后0天的PM10相对风险PI为15%,滞后1天的NO2相对风险PI为7个百分点。

结论

有证据表明,在一个受甘蔗焚烧空气污染影响的地区的中等城市,空气污染物对肺炎住院有影响,此处提供的数据为实施旨在降低这种风险的公共政策提供了支持。

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