Jeandel A, Thibaud J L, Blot S
Neurology Unit & UPR de Neurobiologie, Ecole nationale vétérinaire d'Alfort, Université Paris-Est Créteil, 94700 Maisons Alfort, France.
Micen-Vet, 94000 Créteil, France.
J Small Anim Pract. 2016 Feb;57(2):74-8. doi: 10.1111/jsap.12428. Epub 2016 Jan 19.
The aim of this study was to describe the signalment, clinical presentation, diagnostic findings and long-term follow-up in dogs with concomitant facial and vestibular neuropathy of unknown origin.
Appropriate cases were located through medical record searches. Inclusion criteria comprised dogs that had: clinical signs of facial paralysis with concomitant peripheral vestibular syndrome, thyroid function tests, no abnormalities on magnetic resonance imaging of the brain and tympanic bullae, and cerebrospinal fluid analysis.
Sixteen dogs met the inclusion criteria. Facial paralysis had acute onset (<24 hours) in all dogs, thyroid function was within normal limits. There was albuminocytologic dissociation in cerebrospinal fluid of 69% of the dogs. There was complete resolution of clinical signs in 31% of the dogs but 38% showed long-term vestibular deficits, 46% developed hemifacial contracture, 15% had permanent facial paralysis and 15% relapsed.
Facial and vestibular neuropathy of unknown origin shares similarities with idiopathic facial paralysis. The prognosis for return of normal facial and vestibular function is guarded and there may be relapse after recovery.
本研究旨在描述病因不明的伴有面部和前庭神经病变的犬只的特征、临床表现、诊断结果及长期随访情况。
通过病历检索确定合适的病例。纳入标准包括患有以下情况的犬只：伴有外周前庭综合征的面瘫临床症状、甲状腺功能测试、脑部和鼓室的磁共振成像无异常以及脑脊液分析。
16只犬符合纳入标准。所有犬的面瘫均急性发作（<24小时），甲状腺功能在正常范围内。69%的犬脑脊液存在蛋白细胞分离现象。31%的犬临床症状完全缓解，但38%表现出长期前庭功能缺损，46%出现半面痉挛，15%有永久性面瘫，15%复发。
病因不明的面部和前庭神经病变与特发性面瘫有相似之处。面部和前庭功能恢复正常的预后情况不容乐观，恢复后可能会复发。
