地枫皮茎皮中的木脂素糖苷

Lignan Glucosides from the Stem Barks of Illicium difengpi.

作者信息

Pan Zheng-Hong, Ning De-Sheng, Huang Si-Si, Cheng Ling, Xia Meng-Wen, Peng Li-Yan, Li Dian-Peng

机构信息

Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin 541006, China.

Faculty of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, China.

出版信息

Molecules. 2016 May 10;21(5):607. doi: 10.3390/molecules21050607.

DOI:10.3390/molecules21050607

PMID:27171070

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6273417/

Abstract

In this study, four new lignan glucosides, named difengpiosides A-D (1-4), were isolated from the stem barks of Illicium difengpi, together with seven known compounds 5-11. Their structures were identified on the basis of spectroscopic analyses (1D and 2D NMR, HRESIMS, CD) and a comparison with literature data. All the compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells.

摘要

在本研究中，从地枫皮的茎皮中分离出四种新的木脂素苷，命名为地枫皮苷A-D（1-4），以及七种已知化合物5-11。通过光谱分析（一维和二维核磁共振、高分辨电喷雾电离质谱、圆二色光谱）并与文献数据进行比较确定了它们的结构。评估了所有化合物对脂多糖（LPS）诱导的RAW264.7细胞中一氧化氮（NO）生成的抑制作用。