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药用大麻在临床治疗中的作用:药剂师的观点。

The Role of Medicinal Cannabis in Clinical Therapy: Pharmacists' Perspectives.

作者信息

Isaac Sami, Saini Bandana, Chaar Betty B

机构信息

Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.

出版信息

PLoS One. 2016 May 12;11(5):e0155113. doi: 10.1371/journal.pone.0155113. eCollection 2016.

Abstract

BACKGROUND

Medicinal cannabis has recently attracted much media attention in Australia and across the world. With the exception of a few countries, cannabinoids remain illegal-known for their adverse effects rather than their medicinal application and therapeutic benefit. However, there is mounting evidence demonstrating the therapeutic benefits of cannabis in alleviating neuropathic pain, improving multiple sclerosis spasticity, reducing chemotherapy induced nausea and vomiting, and many other chronic conditions. Many are calling for the legalisation of medicinal cannabis including consumers, physicians and politicians. Pharmacists are the gatekeepers of medicines and future administrators/dispensers of cannabis to the public, however very little has been heard about pharmacists' perspectives. Therefore the aim of this study was to explore pharmacists' views about medicinal cannabis; its legalisation and supply in pharmacy.

METHODS

Semi-structured interviews with 34 registered pharmacists in Australia were conducted. All interviews were audio-recorded, transcribed ad verbatim and thematically analysed using the NVivo software.

RESULTS

Emergent themes included stigma, legislation, safety and collaboration. Overall the majority of pharmacists felt national legalisation of a standardised form of cannabis would be suitable, and indicated various factors and strategies to manage its supply. The majority of participants felt that the most suitable setting would be via a community pharmacy setting due to the importance of accessibility for patients.

DISCUSSION

This study explored views of practicing pharmacists, revealing a number of previously undocumented views and barriers about medicinal cannabis from a supply perspective. There were several ethical and professional issues raised for consideration. These findings highlight the important role that pharmacists hold in the supply of medicinal cannabis. Additionally, this study identified important factors, which will help shape future policies for the successful implementation of medicinal cannabis in healthcare. We recommend that these views and strategies be incorporated in the development of policies and legislations.

摘要

背景

药用大麻最近在澳大利亚乃至全球都引起了媒体的广泛关注。除了少数几个国家外,大麻素仍然是非法的——人们更多地知晓其副作用,而非其药用价值和治疗益处。然而,越来越多的证据表明,大麻在缓解神经性疼痛、改善多发性硬化症痉挛、减轻化疗引起的恶心和呕吐以及许多其他慢性病方面具有治疗益处。包括消费者、医生和政治家在内的许多人都呼吁将药用大麻合法化。药剂师是药品的把关人,也是未来向公众供应/配发大麻的人员,然而关于药剂师的观点却鲜有所闻。因此,本研究的目的是探讨药剂师对药用大麻的看法;其合法化以及在药房的供应情况。

方法

对澳大利亚34名注册药剂师进行了半结构化访谈。所有访谈都进行了录音,逐字转录,并使用NVivo软件进行了主题分析。

结果

浮现出的主题包括污名化、立法、安全性和协作。总体而言,大多数药剂师认为标准化形式的大麻在全国范围内合法化是合适的,并指出了管理其供应的各种因素和策略。大多数参与者认为,由于对患者来说可及性很重要,最合适的供应场所是社区药房。

讨论

本研究探讨了执业药剂师的观点,从供应角度揭示了一些此前未被记录的关于药用大麻的观点和障碍。还提出了一些伦理和专业问题以供考虑。这些发现凸显了药剂师在药用大麻供应中所起的重要作用。此外,本研究确定了重要因素,这将有助于塑造未来在医疗保健中成功实施药用大麻的政策。我们建议将这些观点和策略纳入政策和立法的制定过程中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd43/4865212/236a31ed6afa/pone.0155113.g001.jpg

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