Corrado Giacomo, Cutillo Giuseppe, Mancini Emanuela, Baiocco Ermelinda, Patrizi Lodovico, Saltari Maria, di Luca Sidozzi Anna, Sperduti Isabella, Pomati Giulia, Vizza Enrico
Surgical Oncology Department, Gynecologic Oncology Unit, Regina Elena National Cancer Institute, Rome, Italy.
Surgery Department, Section of Gynecology and Obstetrics, Tor Vergata University, Rome, Italy.
J Gynecol Oncol. 2016 Jul;27(4):e39. doi: 10.3802/jgo.2016.27.e39.
To compare surgical outcomes and cost of robotic single-site hysterectomy (RSSH) versus robotic multiport hysterectomy (RMPH) in early stage endometrial cancer.
This is a retrospective case-control study, comparing perioperative outcomes and costs of RSSH and RMPH in early stage endometrial cancer patients. RSSH were matched 1:2 according to age, body mass index, comorbidity, the International Federation of Gynecology and Obstetric (FIGO) stage, type of radical surgery, histologic type, and grading. Mean hospital cost per discharge was calculated summarizing the cost of daily hospital room charges, operating room, cost of supplies and length of hospital stay.
A total of 23 women who underwent RSSH were matched with 46 historic controls treated by RMPH in the same institute, with the same surgical team. No significant differences were found in terms of age, histologic type, stage, and grading. Operative time was similar: 102.5 minutes in RMPH and 110 in RSSH (p=0.889). Blood loss was lower in RSSH than in RMPH (respectively, 50 mL vs. 100 mL, p=0.001). Hospital stay was 3 days in RMPH and 2 days in RSSH (p=0.001). No intraoperative complications occurred in both groups. Early postoperative complications were 2.2% in RMPH and 4.3% in RSSH. Overall cost was higher in RMPH than in RSSH (respectively, $7,772.15 vs. $5,181.06).
Our retrospective study suggests the safety and feasibility of RSSH for staging early endometrial cancer without major differences from the RMPH in terms of surgical outcomes, but with lower hospital costs. Certainly, further studies are eagerly warranted to confirm our findings.
比较早期子宫内膜癌患者行机器人单孔腹腔镜子宫切除术(RSSH)与机器人多孔腹腔镜子宫切除术(RMPH)的手术效果及费用。
这是一项回顾性病例对照研究,比较早期子宫内膜癌患者行RSSH和RMPH的围手术期结局及费用。根据年龄、体重指数、合并症、国际妇产科联盟(FIGO)分期、根治性手术类型、组织学类型和分级,将RSSH患者与RMPH患者按1:2进行匹配。计算每次出院的平均住院费用,汇总每日住院病房费用、手术室费用、耗材费用和住院时间。
共有23例行RSSH的女性与同一机构、同一手术团队治疗的46例接受RMPH的历史对照患者进行匹配。在年龄、组织学类型、分期和分级方面未发现显著差异。手术时间相似:RMPH为102.5分钟,RSSH为110分钟(p = 0.889)。RSSH的失血量低于RMPH(分别为50 mL对100 mL,p = 0.001)。RMPH的住院时间为3天,RSSH为2天(p = 0.001)。两组均未发生术中并发症。术后早期并发症在RMPH中为2.2%,在RSSH中为4.3%。RMPH的总体费用高于RSSH(分别为7772.15美元对5181.06美元)。
我们的回顾性研究表明,RSSH用于早期子宫内膜癌分期具有安全性和可行性,在手术效果方面与RMPH无重大差异,但住院费用较低。当然,迫切需要进一步的研究来证实我们的发现。