免疫重建炎症综合征、人类疱疹病毒8型病毒血症与HIV相关多中心Castleman病

Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease.

作者信息

Siegel Marc O, Ghafouri Sanaz, Ajmera Ravi, Simon Gary L

机构信息

Division of Infectious Diseases, George Washington University School of Medicine and Health Sciences, 150 Pennsylvania Avenue, NW, Washington, DC 20037, USA.

George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

出版信息

Int J Infect Dis. 2016 Jul;48:49-51. doi: 10.1016/j.ijid.2016.05.005. Epub 2016 May 9.

DOI:10.1016/j.ijid.2016.05.005

PMID:27173076

Abstract

Kaposi's sarcoma and multicentric Castleman Disease are HIV-related disease processes that are associated with human herpesvirus 8 (HHV-8) infection. The development of multicentric Castleman disease can often be a manifestation of the immune reconstitution inflammatory syndrome phenomenon and is associated with markedly elevated levels of HHV-8 viremia, as illustrated by this case.

摘要

卡波西肉瘤和多中心性Castleman病是与人类免疫缺陷病毒（HIV）相关的疾病进程，与人类疱疹病毒8型（HHV - 8）感染有关。如本病例所示，多中心性Castleman病的发展通常是免疫重建炎症综合征现象的一种表现，并且与HHV - 8病毒血症水平显著升高有关。