Hansen Thea Toft, Jakobsen Tine Anette, Nielsen Mette Søndergaard, Sjödin Anders, Le Roux Carel W, Schmidt Julie Berg
Department of Nutrition, Exercise and Sports, Faculty of Science (Obesity Research), University of Copenhagen, Rolighedsvej 26, 1958, Frederiksberg C, Denmark.
Odense University Hospital, The Danish Diabetes Academy, Sdr Boulevard 29, 5000, Odense C, Denmark.
Obes Surg. 2016 Aug;26(8):1946-55. doi: 10.1007/s11695-016-2217-x.
It has been suggested that a shift in food choices leading to a diet with a lower energy density plays an important role in successful weight loss after Roux-en-Y gastric bypass (RYGB) surgery. A decreased hedonic drive to consume highly palatable foods may explain these changes in eating behavior. Here, we review the literature examining postoperative changes in mechanisms contributing to hedonic drive (food preferences, reinforcing value of food, dopamine signaling, and activity reward-related brain regions). The majority of studies reviewed support that RYGB decrease the hedonic drive to consume highly palatable foods. Still, in order to fully understand the complexity of these changes, we need studies combining sociological and psychological approaches with objective measures of actual food choices examining different measures of hedonic drive.
有人认为,食物选择的转变导致能量密度较低的饮食,在Roux-en-Y胃旁路术(RYGB)后成功减重中起着重要作用。对高适口性食物的享乐驱动力降低可能解释了这些饮食行为的变化。在此,我们回顾了研究术后享乐驱动力相关机制(食物偏好、食物强化价值、多巴胺信号以及与活动奖励相关的脑区)变化的文献。大多数综述研究支持RYGB会降低对高适口性食物的享乐驱动力。然而,为了全面理解这些变化的复杂性,我们需要将社会学和心理学方法与实际食物选择的客观测量相结合的研究,以考察享乐驱动力的不同测量指标。