痘苗病毒L-IVP株全基因组序列
Complete Genome Sequence of Vaccinia Virus Strain L-IVP.
作者信息
Shvalov Alexander N, Sivolobova Galina F, Kuligina Elena V, Kochneva Galina V
机构信息
State Research Center of Virology and Biotechnology "Vector," Koltsovo, Novosibirsk Region, Russia.
State Research Center of Virology and Biotechnology "Vector," Koltsovo, Novosibirsk Region, Russia Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
出版信息
Genome Announc. 2016 May 12;4(3):e00372-16. doi: 10.1128/genomeA.00372-16.
Abstract
Most of the live vaccine doses of vaccinia virus donated to the Intensified Smallpox Eradication Programme after 1971 were prepared using the L-IVP strain. A mixture of three clones of the L-IVP strain was sequenced using MySEQ. Consensus sequence similarity with the vaccinia virus Lister strain is 99.5%.
摘要
1971年后捐赠给强化天花根除计划的大多数痘苗病毒活疫苗剂量是使用L-IVP毒株制备的。使用MySEQ对L-IVP毒株的三个克隆混合物进行了测序。与痘苗病毒李斯特毒株的共有序列相似度为99.5%。
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