Shi Xiaoqing, Wang Xiaoqin, Wang Chuan, Zhou Kaiyu, Li Yifei, Hua Yimin
From the Department of Pediatrics (XS, XW, CW, KZ, YL, YH), West China Second University Hospital, Sichuan University; Key Laboratory of Ministry of Education for Women and Children's Diseases and Birth Defects (XS, XW, CW, KZ, YL, YH), West China Second University Hospital, Sichuan University; and The Changjiang Scholar Program and Innovative Research Team in University (KZ, YH), West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Medicine (Baltimore). 2016 May;95(19):e3358. doi: 10.1097/MD.0000000000003358.
Pulmonary artery dissection (PAD) is a rare condition with high mortality and has not been reported in patient with infective endocarditis (IE). Here, we report the first case of such patient who experienced PDA and survived after surgical intervention.A 10-year-old female child was diagnosed as IE with a patent ductus arteriosis (PDA) and a vegetation on the left side of pulmonary artery trunk (10 × 5 mm). Following 3-week antibacterial treatment, the body temperature of patient returned to normal, and the size of vegetation reduced (7 × 3 mm). However, the patient had a sudden attack of sustained and crushing right chest pain, orthopnea with increasing respiratory rate (> 60/min), and acute high fever. Echocardiography revealed the detachment of vegetation on the first day and dissection of pulmonary artery on the next day. The patient received immediate surgical intervention. It was found that aneurysm had a size of 28 × 20 mm and its orifice (the dissecting site) located on the opposite side of the PDA opening (right side of the pulmonary artery trunk). The dissected left wall of pulmonary artery trunk was reconstructed followed by the closure of PDA with suture. The patient recovered uneventfully.From this case, we learned that the surgical intervention should be considered at an early time for IE patients who have a vegetation in pulmonary artery and PDA. After the infection is under control, the earlier surgery may prevent severe complications.
肺动脉夹层(PAD)是一种罕见但死亡率高的疾病,感染性心内膜炎(IE)患者中尚未有相关报道。在此,我们报告首例发生肺动脉夹层且经手术干预后存活的此类患者。一名10岁女童被诊断为患有动脉导管未闭(PDA)及肺动脉主干左侧赘生物(10×5mm)的感染性心内膜炎。经过3周抗菌治疗后,患者体温恢复正常,赘生物大小缩小(7×3mm)。然而,患者突然发作持续性压榨性右胸痛、呼吸急促(呼吸频率>60次/分钟)伴急性高热。超声心动图显示第一天赘生物脱落,第二天肺动脉夹层形成。患者立即接受手术干预。术中发现动脉瘤大小为28×20mm,其开口(夹层部位)位于动脉导管未闭开口的对侧(肺动脉主干右侧)。对肺动脉主干剥离的左壁进行重建,随后用缝线闭合动脉导管未闭。患者恢复顺利。从该病例中我们了解到,对于患有肺动脉赘生物和动脉导管未闭的感染性心内膜炎患者,应尽早考虑手术干预。在感染得到控制后,尽早手术可预防严重并发症。