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八只患有动脉导管未闭的犬的肺动脉夹层。

Pulmonary artery dissection in eight dogs with patent ductus arteriosus.

作者信息

Scansen Brian A, Simpson Elaine M, López-Alvarez Jordi, Thomas William P, Bright Janice M, Eason Bryan D, Rush John E, Dukes-McEwan Joanna, Green Henry W, Cunningham Suzanne M, Visser Lance C, Kent Agnieszka M, Schober Karsten E

机构信息

Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA.

Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA.

出版信息

J Vet Cardiol. 2015 Jun;17(2):107-19. doi: 10.1016/j.jvc.2014.12.001. Epub 2015 Jan 14.

Abstract

OBJECTIVES

To describe a series of dogs with pulmonary artery dissection and patent ductus arteriosus (PDA).

ANIMALS

Eight dogs.

METHODS

Retrospective case series.

RESULTS

Pulmonary artery dissection was diagnosed in 8 dogs, 3 were Weimaraners. Four dogs presented in left-sided congestive heart failure, 4 presented for murmur evaluation and without clinical signs, and 1 presented in right-sided congestive heart failure. In 7 dogs the dissection was first documented concurrent with a diagnosis of uncorrected PDA. In the other dog, with pulmonary valve stenosis and PDA, the dissection was observed on autopsy examination 17 months after balloon pulmonary valvuloplasty and ductal closure. Median age at presentation for the 7 dogs with antemortem diagnosis of pulmonary artery dissection was 3.5 years (range, 1.5-4 years). Three dogs had the PDA surgically ligated, 2 dogs did not undergo PDA closure, 1 dog failed transcatheter occlusion of the PDA with subsequent surgical ligation, 1 dog underwent successful transcatheter device occlusion of the PDA, and 1 dog had the PDA closed by transcatheter coil delivery 17 months prior to the diagnosis of pulmonary artery dissection. The 2 dogs that did not have the PDA closed died 1 and 3 years after diagnosis due to heart failure.

CONCLUSIONS

Pulmonary artery dissection is a potential complication of PDA in dogs, the Weimaraner breed may be at increased risk, presentation is often in mature dogs, and closure of the PDA can be performed and appears to improve outcome.

摘要

目的

描述一系列患有肺动脉夹层和动脉导管未闭(PDA)的犬只。

动物

8只犬。

方法

回顾性病例系列研究。

结果

8只犬被诊断为肺动脉夹层,其中3只为魏玛犬。4只犬表现为左侧充血性心力衰竭,4只犬因杂音评估就诊且无临床症状,1只犬表现为右侧充血性心力衰竭。7只犬的夹层首次记录于未纠正的PDA诊断同时。另一只患有肺动脉瓣狭窄和PDA的犬,在球囊肺动脉瓣成形术和导管闭合术后17个月尸检时发现夹层。7只生前诊断为肺动脉夹层的犬就诊时的中位年龄为3.5岁(范围1.5 - 4岁)。3只犬接受了PDA手术结扎,2只犬未进行PDA闭合,1只犬经导管封堵PDA失败后进行了手术结扎,1只犬经导管成功封堵PDA,1只犬在诊断肺动脉夹层前17个月通过经导管输送线圈闭合了PDA。2只未闭合PDA的犬在诊断后1年和3年因心力衰竭死亡。

结论

肺动脉夹层是犬PDA的一种潜在并发症,魏玛犬品种可能风险增加,发病通常见于成年犬,PDA闭合可以进行且似乎能改善预后。

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