Smirnov G A, Fattakhova R M, Valiev R Sh, Trofimova R I, Gazizullina N K
Probl Tuberk. 1989(1):24-7.
Three hundred and eighty seven patients with pulmonary tuberculosis having single or multiple destructive cavities less than 2 cm in size were observed. Two thirds of the caverns became undetectable 2-4 months after the therapy start. The roentgenograms of the patients were analyzed, the time courses of the caverns were compared with those of lung tuberculomas of the same size and the disease outcomes were estimated. It was concluded that in the cases with small cavities not closing for prolonged periods tuberculomas with destructions in the infiltrate depth or caseous foci with their partial resolution might be suspected. It was indicated that tuberculin therapy increased the frequency of small cavern healing though their significant part closed at late periods which requires development of more efficient methods for their medication. On the whole, the outcomes of pulmonary tuberculosis with minimal destruction of the lung tissue were favourable. The disease progress was stated only in the patients who did not complete the treatment course.
观察了387例患有单个或多个大小小于2厘米的破坏性空洞的肺结核患者。三分之二的空洞在治疗开始后2至4个月变得无法检测到。分析了患者的X线胸片,将空洞的病程与相同大小的肺结核瘤的病程进行了比较,并评估了疾病的转归。得出的结论是,对于长时间不闭合的小空洞病例,可能怀疑有浸润深度有破坏的结核瘤或有部分溶解的干酪样病灶。结果表明,结核菌素疗法增加了小空洞愈合的频率,尽管其中很大一部分在后期才闭合,这需要开发更有效的药物治疗方法。总体而言,肺组织破坏最小的肺结核患者的转归良好。仅在未完成治疗疗程的患者中出现了疾病进展。