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MFM肥胖方案对剖宫产率的影响。

The effect of the MFM obesity protocol on cesarean delivery rates.

作者信息

Schuster Meike, Madueke-Laveaux Obianuju Sandra, Mackeen A Dhanya, Feng Wen, Paglia Michael J

机构信息

Department of Maternal-Fetal Medicine, Women's Health Service Line, Geisinger Health System, Danville, PA.

Department of Obstetrics and Gynecology, Columbia University, New York, NY.

出版信息

Am J Obstet Gynecol. 2016 Oct;215(4):492.e1-6. doi: 10.1016/j.ajog.2016.05.005. Epub 2016 May 10.

Abstract

BACKGROUND

Obesity in pregnancy has an impact on both the mother and the fetus. To date, no universal protocol has been established to guide the management of pregnancy in obese woman. In April 2011, the Geisinger Maternal-Fetal Medicine Department implemented an obesity protocol in which women meeting the following criteria were delivered by their estimated due dates: (1) class III obese or (2) class II obese with additional diagnoses of a large-for-gestational-age fetus or pregnancy complicated by gestational diabetes or (3) class I obese with large-for-gestational-age and gestational diabetes.

OBJECTIVE

We sought to assess the impact of this protocol on the rate of cesarean deliveries in obese women.

STUDY DESIGN

We performed a retrospective cohort study of 5000 randomly selected women who delivered at Geisinger between January 2009 and September 2013, excluding those who delivered in 2011. The data were stratified into obese and nonobese and divided into before protocol and after protocol. Comparison across all groups was accomplished using Wilcoxon rank sum and Pearson's χ(2) tests. Potential confounders were controlled for using logistic regression.

RESULTS

The cesarean delivery rate in the obese/after protocol group was 10.8% lower than in the obese/before protocol group (42.4% vs 31.6%, respectively; P < .0001). In addition, when controlling for age, race, smoking status, preeclampsia, gestational diabetes, and intrauterine growth restriction, obese women were 37% less likely to have a cesarean delivery after the protocol than they were before (odds ratio, 0.63; 95% confidence interval, 0.52, 0.76, P < .0001).

CONCLUSION

Implementation of a maternal-fetal medicine obesity protocol did not increase the rate of cesarean deliveries in obese women. On the contrary, obese women were less likely to have a cesarean delivery after implementation of the protocol.

摘要

背景

妊娠期肥胖对母亲和胎儿均有影响。迄今为止,尚未建立通用方案来指导肥胖女性的孕期管理。2011年4月,盖辛格母婴医学科实施了一项肥胖方案,符合以下标准的女性按其预计预产期分娩:(1)Ⅲ级肥胖;或(2)Ⅱ级肥胖且伴有巨大胎儿或妊娠期糖尿病合并妊娠的额外诊断;或(3)Ⅰ级肥胖且伴有巨大胎儿和妊娠期糖尿病。

目的

我们试图评估该方案对肥胖女性剖宫产率的影响。

研究设计

我们对2009年1月至2013年9月在盖辛格分娩的5000名随机选择的女性进行了回顾性队列研究,排除2011年分娩的女性。数据分为肥胖组和非肥胖组,并分为方案实施前和方案实施后。使用Wilcoxon秩和检验和Pearson卡方检验对所有组进行比较。使用逻辑回归控制潜在混杂因素。

结果

肥胖/方案实施后组的剖宫产率比肥胖/方案实施前组低10.8%(分别为42.4%和31.6%;P<.0001)。此外,在控制年龄、种族、吸烟状况、先兆子痫、妊娠期糖尿病和胎儿生长受限后,肥胖女性在方案实施后进行剖宫产的可能性比之前低37%(比值比,0.63;95%置信区间,0.52,0.76,P<.0001)。

结论

实施母婴医学肥胖方案并未增加肥胖女性的剖宫产率。相反,方案实施后肥胖女性进行剖宫产的可能性较小。

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