Madanat Rami, Rolfson Ola, Donahue Gabrielle S, Hussey Daniel K, Potter Hollis G, Wallace Robert, Muratoglu Orhun K, Malchau Henrik
Harris Orthopaedic Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts; Department of Orthopaedic Surgery, Harvard Medical School, Boston, Massachusetts.
Harris Orthopaedic Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.
J Arthroplasty. 2016 Nov;31(11):2588-2592. doi: 10.1016/j.arth.2016.04.005. Epub 2016 Apr 13.
Medial calcar erosion is considered a late finding in patients with severe adverse local tissue reactions (ALTRs) after total hip arthroplasty (THA) with dual modular neck stems. Although calcar erosion has been associated with dual modular neck stems, one would expect similar findings in standard stems owing to analogous corrosion at the taper junction. The aim of this study was to evaluate whether medial calcar erosion is also associated with ALTR in patients with standard stems in metal-on-metal (MoM) THA.
A total of 96 patients (108 hips) with MoM THA had radiographs and a magnetic resonance imaging of the hip performed at a mean time of 5.7 years after surgery. Calcar erosion was assessed from radiographs. ALTR Anderson grade, diameter, volume, and synovial thickness were assessed from magnetic resonance imaging.
Calcar erosion was present in 54 hips (50%) and was associated with ALTR synovial thickness but not with Anderson grade, diameter, or volume. Most of the hips with calcar erosion (n = 45) had an ALTR (positive predictive value 0.83, 95% confidence interval 0.70-0.92). The relative risk of having a synovial thickness > 3 mm increased by a factor of 3.0 (95% confidence interval 1.3-6.5) if calcar erosion was observed.
Subtle erosions of the medial calcar after MoM THA may be an early indicator of an adverse reaction to wear particles warranting cross-sectional imaging. Synovial thickness may also be more relevant than absolute size in the classification of ALTR severity and collateral tissue damage.
在内侧股骨距骨侵蚀被认为是使用双模块化颈柄进行全髋关节置换术(THA)后出现严重局部组织不良反应(ALTR)患者的晚期表现。尽管距骨侵蚀与双模块化颈柄有关,但由于锥度连接处类似的腐蚀情况,人们预计在标准柄中也会出现类似的发现。本研究的目的是评估在金属对金属(MoM)全髋关节置换术中,内侧股骨距骨侵蚀是否也与使用标准柄的患者的ALTR相关。
共有96例(108髋)接受MoM全髋关节置换术的患者在术后平均5.7年时进行了髋关节X线片和磁共振成像检查。通过X线片评估距骨侵蚀情况。通过磁共振成像评估ALTR安德森分级、直径、体积和滑膜厚度。
54髋(50%)存在距骨侵蚀,且与ALTR滑膜厚度相关,但与安德森分级、直径或体积无关。大多数有距骨侵蚀的髋关节(n = 45)存在ALTR(阳性预测值0.83,95%置信区间0.70 - 0.92)。如果观察到距骨侵蚀,滑膜厚度> 3 mm的相对风险增加3.0倍(95%置信区间1.3 - 6.5)。
MoM全髋关节置换术后内侧股骨距的细微侵蚀可能是对磨损颗粒不良反应的早期指标,需要进行横断面成像检查。在ALTR严重程度和侧支组织损伤的分类中,滑膜厚度可能比绝对大小更具相关性。