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嗜酸性膀胱炎与血尿:一种罕见疾病及常见表现的病例报告

Eosinophilic cystitis and haematuria: Case report of a rare disease and common presentation.

作者信息

Chia Daniel

机构信息

Department of Urology, Westmead Hospital, Corner of Hawkesbury Road and Darcy Road, Westmead, Sydney, NSW, 2145, Australia.

出版信息

Int J Surg Case Rep. 2016;24:43-5. doi: 10.1016/j.ijscr.2016.04.055. Epub 2016 May 6.

DOI:10.1016/j.ijscr.2016.04.055
PMID:27179336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4873027/
Abstract

INTRODUCTION

Eosinophilic cystitis is a rare inflammatory condition of the bladder that can cause haematuria. The aetiology is unknown and clinical presentation is difficult to distinguish from other causes of haematuria. Diagnosis is confirmed by biopsy. In this case, a patient with haematuria is diagnosed with eosinohpilic cystitis after presenting to hospital. He was commenced on antibiotics for a presumed urinary tract infection with no resolution of haematuria and symptoms. After diagnosis he was commenced on treatment with resolution of symptoms.

CASE PRESENTATION

A 73-year-old male presents with first episode of haematuria. He was initially diagnosed with a urinary tract infection and commenced on antibiotics with no resolution. After further investigations including a cystoscopy and bladder biopsy, he was diagnosed with eosinophilic cystitis. He was treated with steroids improving his symptoms.

CONCLUSION

Eosinophilic cystitis is a rare disease of the bladder which is difficult to distinguish from other causes of haematuria, and is often misdiagnosed. Bladder biopsy is necessary for diagnosis. Early diagnosis is important, and it is through a combination of non-operative and operative interventions such as biopsy. Natural history is difficult to predict as it is difficult to determine is a patient will have a benign course with resolution with or without treatment, or result in a chronic course which may result in bladder damage and renal failure. This case highlights the importance of investigating haematuria that is unresponsive to initial empiric treatment such as antibiotics. It is important to refer to a Urologist for further investigation to rule out a sinister cause, but to also obtain a diagnosis, leading to definitive treatment.

摘要

引言

嗜酸性膀胱炎是一种罕见的膀胱炎症性疾病,可导致血尿。其病因不明,临床表现难以与其他血尿原因相区分。通过活检确诊。在本病例中,一名血尿患者入院后被诊断为嗜酸性膀胱炎。他因疑似尿路感染开始使用抗生素治疗,但血尿和症状未缓解。诊断后开始治疗,症状得以缓解。

病例介绍

一名73岁男性首次出现血尿。他最初被诊断为尿路感染并开始使用抗生素,但症状未缓解。经过包括膀胱镜检查和膀胱活检在内的进一步检查,他被诊断为嗜酸性膀胱炎。他接受了类固醇治疗,症状有所改善。

结论

嗜酸性膀胱炎是一种罕见的膀胱疾病,难以与其他血尿原因相区分,且常被误诊。膀胱活检对于诊断是必要的。早期诊断很重要,这需要通过活检等非手术和手术干预相结合的方式。其自然病程难以预测,因为很难确定患者是会在接受或不接受治疗的情况下良性缓解,还是会发展为慢性病程,进而可能导致膀胱损伤和肾衰竭。本病例强调了对初始经验性治疗(如抗生素治疗)无反应的血尿进行检查的重要性。重要的是转诊给泌尿科医生进行进一步检查,以排除恶性病因,并获得诊断,从而进行明确治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef1f/4873027/b21271ddf312/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef1f/4873027/b21271ddf312/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef1f/4873027/b21271ddf312/gr1.jpg

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