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种族对晚期慢性静脉功能不全的影响。

The Impact of Race on Advanced Chronic Venous Insufficiency.

作者信息

Dua Anahita, Desai Sapan S, Heller Jennifer A

机构信息

Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.

Department of Vascular Surgery, Southern Illinois University, Springfield, IL.

出版信息

Ann Vasc Surg. 2016 Jul;34:152-6. doi: 10.1016/j.avsg.2016.01.020. Epub 2016 May 12.

Abstract

BACKGROUND

The study aimed to determine the association between race and patient variables, hospital covariates, and outcomes in patients presenting with advanced chronic venous insufficiency.

METHODS

The National Inpatient Sample was queried to identify all Caucasian and African-American patients with a primary International Classification of Diseases, Ninth Revision (ICD-9) diagnosis code for venous stasis with ulceration (454.0), inflammation (454.1), or complications (454.2) from 1998 to 2011. CEAP scores were correlated with ICD-9 diagnosis. Demographics, CEAP classification, management, cost of care, length of stay (LOS), and inpatient mortality were compared between races. Statistical analysis was via descriptive statistics, Student's t-test, and the Fisher's exact test. Trend analysis was completed using the Mann-Kendall test.

RESULTS

A total of 20,648 patients were identified of which 85% were Caucasian and 15% were African-American. Debridement procedures had the highest costs at $6,096 followed by skin grafting at $4,089. There was an overall decrease in the number of ulcer debridements, vein stripping, and sclerotherapy procedures between 1998 and 2011 (P < 0.05) for both groups. However, African-American patients had significantly more ulcer debridements than their Caucasian counterparts.

CONCLUSIONS

African-American patients with a primary diagnosis of venous stasis present with more advanced venous disease at a younger age compared with their Caucasian counterparts. This is associated with increased ulcer debridement, deep vein thrombosis rates and hospital charges in the African-American cohort. There are no differences in sclerotherapy or skin grafting procedures, LOS or inpatient mortality between races.

摘要

背景

本研究旨在确定种族与患者变量、医院协变量以及晚期慢性静脉功能不全患者预后之间的关联。

方法

查询国家住院患者样本,以识别1998年至2011年期间所有患有原发性国际疾病分类第九版(ICD-9)诊断代码为静脉淤滞伴溃疡(454.0)、炎症(454.1)或并发症(454.2)的白种人和非裔美国患者。CEAP评分与ICD-9诊断相关。比较了不同种族之间的人口统计学、CEAP分类、治疗管理、护理费用、住院时间(LOS)和住院死亡率。统计分析采用描述性统计、学生t检验和费舍尔精确检验。使用曼-肯德尔检验完成趋势分析。

结果

共识别出20648例患者,其中85%为白种人,15%为非裔美国人。清创手术费用最高,为6096美元,其次是皮肤移植,为4089美元。1998年至2011年期间,两组的溃疡清创、静脉剥脱和硬化疗法手术数量总体均有所下降(P<0.05)。然而,非裔美国患者的溃疡清创手术明显多于白种人患者。

结论

与白种人患者相比,以静脉淤滞为主要诊断的非裔美国患者在更年轻的年龄就出现了更严重的静脉疾病。这与非裔美国人群中溃疡清创、深静脉血栓形成率和住院费用增加有关。不同种族在硬化疗法或皮肤移植手术、住院时间或住院死亡率方面没有差异。

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