Pan Jin, Wang Meng, Ye Zhen, Yu Min, Shen Yuhua, He Qinfang, Cao Naxin, Ning Guang, Bi Yufang, Gong Weiwei, Hu Ruying
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Jiashan Center for Disease Control and Prevention, Jiashan, China.
J Diabetes Investig. 2016 Jul;7(4):594-600. doi: 10.1111/jdi.12440. Epub 2016 Jan 5.
AIMS/INTRODUCTION: The aim of the present study was to compare the cut-off values and prediction effect of different obesity indices by different definitions of metabolic syndrome (MetS) in Zhejiang Province of China.
We carried out a cross-sectional survey of 10,100 individuals (age 40 years and older) in Jiashan, Zhejiang Province. Receiver operating characteristic analysis was used to examine discrimination and find optimal cut off values of waist circumference (WC), body mass index (BMI), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) to predict two or more non-adipose components of MetS by The National Cholesterol Education Program Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) definition modified by the Asia-Pacific region criteria, International Diabetes Federation definition for the Chinese population and Chinese Diabetes Society definitions of MetS.
The age-standardized prevalence of MetS was 23.78% vs 28.76% vs 19.37% by The National Cholesterol Education Program Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III), International Diabetes Federation and Chinese Diabetes Society definitions, respectively. Cut-off values of BMI were approximately 24 kg/m(2) both in men and women by three definitions; the average cut-off values of WC, WHR and WHtR were 83 cm in men vs 81 cm in women, 0.89 in men vs 0.86 in women and 0.50 in men vs 0.51 in women, respectively. The area under receiver operating characteristic curve of BMI was larger than WC both in men and women (P < 0.05); in women, the area under receiver operating characteristic curve of WHtR was larger than WC, and WHR was smaller.
MetS is prevalent in Zhejiang Province of China, especially in the female population. BMI and WHtR might be more useful than WC and WHR for predicting two or more non-adipose components of MetS.
目的/引言：本研究旨在比较在中国浙江省不同代谢综合征（MetS）定义下不同肥胖指数的截断值及预测效果。
我们对浙江省嘉善县10100名40岁及以上个体进行了横断面调查。采用受试者工作特征分析来检验区分能力，并找出腰围（WC）、体重指数（BMI）、腰臀比（WHR）和腰高比（WHtR）的最佳截断值，以根据亚太地区标准修改后的美国国家胆固醇教育计划成人治疗专家组第三次报告（成人治疗小组III）定义、国际糖尿病联盟针对中国人群的定义以及中国糖尿病学会的MetS定义来预测MetS的两个或更多非脂肪成分。
根据美国国家胆固醇教育计划成人治疗专家组第三次报告（成人治疗小组III）、国际糖尿病联盟和中国糖尿病学会的定义，MetS的年龄标准化患病率分别为23.78%、28.76%和19.37%。三种定义下，男性和女性的BMI截断值均约为24kg/m²；WC、WHR和WHtR的平均截断值分别为男性83cm、女性81cm，男性0.89、女性0.86，男性0.50、女性0.51。男性和女性中，BMI的受试者工作特征曲线下面积均大于WC（P<0.05）；在女性中，WHtR的受试者工作特征曲线下面积大于WC，而WHR的则较小。
MetS在中国浙江省普遍存在，尤其是在女性人群中。对于预测MetS的两个或更多非脂肪成分，BMI和WHtR可能比WC和WHR更有用。
