Department of Medicinal and Pharmaceutical Chemistry, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin 2, Ireland.
Chem Soc Rev. 2016 Jul 21;45(14):3846-64. doi: 10.1039/c6cs00200e. Epub 2016 May 16.
Azadipyrromethenes were first described over 70 years ago as blue pigments, but now are rapidly emerging as a compound class with highly desirable near infrared photophysical properties. Since the turn of the century several routes to azadipyrromethenes have been developed and numerous post-synthesis derivatizations have allowed for their exploitation in both biological and material sciences. The relative ease of access to specifically designed derivatives is now allowing their use in multiple technological formats from real-time fluorescence imaging, to solar energy materials, to optoelectronic devices and many more. In this review we have highlighted the synthetic component of this story as it is the ability to generate the designer azadipyrromethene that opens the door to exciting applications.
氮杂二吡咯甲烷类化合物早在 70 多年前就被首次描述为蓝色颜料，但现在作为一类具有理想近红外光物理性质的化合物迅速崛起。自本世纪初以来，已经开发出了几种氮杂二吡咯甲烷类化合物的合成途径，并且许多合成后的衍生化方法使得它们在生物和材料科学领域得到了广泛的应用。现在，人们可以很容易地获得专门设计的衍生物，这使得它们能够应用于多种技术领域，从实时荧光成像到太阳能材料，再到光电设备等等。在这篇综述中，我们强调了这一故事的合成部分，因为正是设计氮杂二吡咯甲烷的能力为令人兴奋的应用开辟了大门。
