犬类新生儿死亡率：静脉导管多普勒波形评估的预后价值——初步结果

Neonatal mortality in dogs: Prognostic value of Doppler ductus venosus waveform evaluation - Preliminary results.

作者信息

Barella Gabriele, Faverzani Stefano, Faustini Massimo, Groppetti Debora, Pecile Alessandro

机构信息

Department of Veterinary Medicine, State University of Milan, Via Celoria 10; 20133; Milan, Italy.

出版信息

Vet World. 2016 Apr;9(4):356-60. doi: 10.14202/vetworld.2016.356-360. Epub 2016 Apr 7.

DOI:10.14202/vetworld.2016.356-360

PMID:27182129

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4864475/

Abstract

AIM

To define the prognostic value of Doppler ultrasonographic morphology of ductus venosus (DV) waveform on canine neonatal mortality.

MATERIALS AND METHODS

Fifty-four healthy pregnant bitches underwent fetal ultrasonographic assessment. The DV waveforms were classified as diphasic (dDVw) or triphasic (tDVw) and compared with neonatal mortality.

RESULTS

Ninety-three fetuses were evaluated. Twenty fetuses belonged to litters with neonatal mortality, in which tDVw was observed. Seven fetuses belonged to litters without neonatal mortality, in which tDVw was observed. Fifty-eight fetuses belonged to litters without neonatal mortality, in which only dDVw was observed. Eight fetuses belonged to litters with neonatal mortality, in which only dDVw was observed. The correlation between tDVw and neonatal mortality was statistically significant (odds ratio [OR], 20.7; p<0.0001). Considering only pregnancies with one or two fetuses with the same DV waveform: Two fetuses with tDVw belonged to litters with neonatal mortality; 1 foetus with tDVw belonged to litter without neonatal mortality and 26 fetuses showed dDVw without neonatal mortality. The correlation between tDVw and neonatal mortality even in litters up to two pups was statistically significant (OR, 88.3; p=0.01).

CONCLUSION

Echo-Doppler assessment of DV is feasible in canine fetuses, and the presence tDVw seems to be related to neonatal mortality.

摘要

目的

确定静脉导管（DV）波形的多普勒超声形态对犬新生儿死亡率的预后价值。

材料与方法

对54只健康怀孕母犬进行胎儿超声评估。将DV波形分为双相（dDVw）或三相（tDVw），并与新生儿死亡率进行比较。

结果

评估了93只胎儿。20只胎儿所属的窝中有新生儿死亡，其中观察到tDVw。7只胎儿所属的窝中无新生儿死亡，其中观察到tDVw。58只胎儿所属的窝中无新生儿死亡，其中仅观察到 dDVw。8只胎儿所属的窝中有新生儿死亡，其中仅观察到dDVw。tDVw与新生儿死亡率之间的相关性具有统计学意义（优势比[OR]，20.7；p<0.0001）。仅考虑有一两个具有相同DV波形胎儿的妊娠：两个具有tDVw的胎儿所属的窝中有新生儿死亡；一个具有tDVw的胎儿所属的窝中无新生儿死亡，26个显示dDVw的胎儿所属的窝中无新生儿死亡。即使在最多有两只幼犬的窝中，tDVw与新生儿死亡率之间的相关性也具有统计学意义（OR，88.3；p = 0.01）。