一名免疫抑制儿童发生肺孢子菌肺炎，病程迁延，支气管肺泡灌洗术结果为GMS阴性。
A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage.
作者信息
Eddens Taylor, Song Eunkyung, Ardura Monica I, Kolls Jay K
机构信息
University of Pittsburgh, RK Mellon Institute for Pediatric Research, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, United States.
Pediatric Infectious Diseases and Immunology, Host Defense Program, Nationwide Children's Hospital and The Ohio State University, Columbus, OH 43205, United States.
出版信息
Med Mycol Case Rep. 2016 Apr 25;11:48-52. doi: 10.1016/j.mmcr.2016.04.004. eCollection 2016 Mar.
We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance. Further, diagnosis of Pneumocystis in this patient was complicated by a GMS-negative bronchoalveolar lavage despite molecular evidence of Pneumocystis infection.
我们报告一例患有21三体综合征和急性淋巴细胞白血病的5岁男性患肺孢子菌肺炎的病例。对甲氧苄啶-磺胺甲恶唑治疗无反应引发了对抗菌素耐药性的担忧。此外，尽管有肺孢子菌感染的分子证据，但该患者的支气管肺泡灌洗吉姆萨染色阴性，使得肺孢子菌的诊断变得复杂。
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