Université Paris Descartes, Service de Maladies Infectieuses et Tropicales, 149 Rue de Sèvres, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker-Enfants Malades, Paris 75015, France.
Infect Dis Clin North Am. 2010 Mar;24(1):107-38. doi: 10.1016/j.idc.2009.10.010.
Pneumocystis jirovecii has gained attention during the last decade in the context of the AIDS epidemic and the increasing use of cytotoxic and immunosuppressive therapies. This article summarizes current knowledge on biology, pathophysiology, epidemiology, diagnosis, prevention, and treatment of pulmonary P jirovecii infection, with a particular focus on the evolving pathophysiology and epidemiology. Pneumocystis pneumonia still remains a severe opportunistic infection, associated with a high mortality rate.
卡氏肺孢子虫在艾滋病流行和细胞毒性及免疫抑制治疗日益广泛应用的背景下，近十年来受到关注。本文总结了卡氏肺孢子虫肺部感染的生物学、发病机制、流行病学、诊断、预防和治疗的最新知识，特别关注不断演变的发病机制和流行病学。卡氏肺孢子虫肺炎仍然是一种严重的机会性感染，死亡率高。
